

The Human Upgrade: Biohacking for Longevity & Performance
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio , he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
Episodes


Your Brain Is 0.5% Plastic (Here’s How to Flush It) : 1426

Why Are Hackers Microdosing “Sex Drugs” Now? : 1425

A-List Celebrities' Anti-Aging Hack to Look 30 At 50 (Drug-free) : 1424

Mexican Cartel Biohacking, Google Anti-Aging Breakthrough, Measles Is Back, Age Reversal In 2026 : 1423

The Secret to Staying DANGEROUS After 50 : 1422
This episode of The Human Upgrade explores the world of peptides, focusing on their applications in longevity, cognitive enhancement, and overall health. Dave Asprey interviews Josh Felber and Jay Campbell, experts in the peptide field, to discuss the basics of peptides, including delivery methods like injectable pens ...

The Home Laser That Reverses Skin Age By 20 Years : 1421

I Tested The Most Dangerous Viral Brain Hack : 1420

Plastic in Your Testicles, AI Sleep Scans, The 29% Weight Loss Drug : 1419

Change Your Morning, Change Your Life – Hal Elrod : 1418
Dave Asprey interviews Hal Elrod, author of "The Miracle Morning," about his updated book, personal resilience, and morning routines. Elrod recounts surviving a near-fatal car accident and later battling cancer, emphasizing the importance of taking responsibility for one's health. They discuss the Miracle Morning's SAV...

The Secret to Looking Younger is in Mushrooms (And Chocolate?) : 1417

Low Testosterone Starts In Your Eyes (Avoid This Before Bed) : 1416

Jet Lag Superdrug, 25% Dementia Drop, Coffee Brain Aging, Kratom Shakeup : 1415

Turn Off Your WiFi Tonight and See What Happens to Your Sleep : 1414

The Secret Peptides and Underground Compounds Doctors Won’t Talk About : 1413
The podcast explores the use of research chemicals, SARMs, and peptides for performance enhancement and overall health, questioning the conventional definitions of "cheating" and "performance-enhancing drugs." Dylan Gemelli, a biohacker, shares his experiences and insights on these substances, alongside host Dave Aspre...

Why Your Muscles Break Down After 40 (Do This To Reverse It) : 1412

Biohackers in the Epstein Files, Generic GLP-1s, Continuous Ketone Monitors, and more... : 1411

Why 18-Year-Olds Wake Up Fresh (And You Don't) : 1410
The discussion centers on stem cell exhaustion as a primary cause of aging and strategies to combat it. Christian Drapeau, a stem cell scientist and neuroscientist, explains that stem cell decline, rather than exhaustion, is a key factor, with red marrow converting to fatty marrow over time. He suggests that a three-da...

STOP Intermittent Fasting If You Want to Stay Young : 1409
The discussion centers on optimizing longevity through diet and lifestyle, challenging conventional wisdom on protein intake and fasting. Valter Longo, gerontology and biological sciences professor, advocates for a longevity diet that includes fasting-mimicking approaches to promote multisystemic regeneration by activa...

Aging Starts In Your Legs (Here’s The Fix) : 1408
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