26 Feb 2026
1h 0m

The Secret to Staying DANGEROUS After 50 : 1422

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The Human Upgrade: Biohacking for Longevity & Performance

This episode of The Human Upgrade explores the world of peptides, focusing on their applications in longevity, cognitive enhancement, and overall health. Dave Asprey interviews Josh Felber and Jay Campbell, experts in the peptide field, to discuss the basics of peptides, including delivery methods like injectable pens and patches, and their potential benefits. The conversation covers specific peptides such as elamipretide (formerly SS-31) for mitochondrial function, MOTS-c for energy, and FLGR 242 for muscle growth and fat loss. They also address safety concerns, the importance of consulting experts, and the regulatory landscape surrounding peptide use, advocating for informed self-experimentation. Additionally, the discussion touches on the anti-aging potential of Klotho and the cognitive benefits of melanin.

Outlines

Part 1: Longevity Compounds and Biohacking Tools

Part 2: Peptide Fundamentals and Delivery Systems

Part 3: Mitochondrial Health and Cellular Signaling

Part 4: Growth Hormones and Muscle Optimization

Part 5: Specialized Support and Skin Protection

Part 6: Advanced Longevity and Future Outlook

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