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Nick Jikomes · Health

Mind & Matter

Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists & thinkers alive today about how your mind-body reacts to what you feed it. The weekly M&M podcast features conversations with the most interesting scientists, thinkers, and technology entrepreneurs alive today. Not medical advice. At M&M, we are interested in trying to figure out how things work, not affirming our existing beliefs. We prefer consulting primary rather than secondary sources and independent rather than institutional voices. If we encounter uncomfortable truths or the evidence suggests unfashionable ideas may be valid, so be it. As the host, my aim is to help you better understand how the body & mind work by curating & synthesizing information in a way that yields science-based insights that you can choose to use or disregard in your own life. Taking ownership of your health starts with taking ownership of your information diet. I am motivated to connect the dots and distill general principles from what I learn, preferring to ask questions and play devil’s advocate to debating or incessantly pushing my own viewpoint. My beliefs: Taking ownership of your health starts with taking ownership of your information diet . All knowledge is provisional and we must work hard to prevent ourselves from becoming attached to our favorite ideas & preferred conclusions. Wisdom comes from an iterative, trial-and-error process of learning and unlearning. Letting go of pre-conceived notions can be painful, but pain is information. Sometimes modern discoveries teach us we must unlearn received wisdom. Other times, modern information overload & historical chauvinism cause us to forget ancient wisdom which stills applies. The framework for learning that I embody is inspired by three Ancient Greek maxims inscribed in the Temple of Apollo at Delphi: “Γνῶθι σεαυτόν” ( Know thyself ) “Μηδὲν ἄγαν” ( Nothing in excess) “Ἐγγύα πάρα δ Ἄτα” ( Certainty brings insanity)

Episodes

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Adipose Tissue & Body Fat: Obesity, Insulin, Leptin, Fertility, Weight Loss & GLP-1 Drugs | Sean Hartig | 174

29 Aug 2024
1h 43m
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Psychedelics, Consciousness, Mental Health & the Entropic Brain | Robin Carhart-Harris | 173

24 Aug 2024
1h 57m
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Immune System, Gut Microbiome, Vitamin D, Cancer, Innate Immunity, Inflammation & Gut-Immune Interactions | Caetano Reis e Sousa | 172

21 Aug 2024
1h 12m
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Comparative Brain Evolution: Mammals, Primates & Humans | Robert Barton | 171

18 Aug 2024
1h 38m
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Sex Differences, Drugs & the Brain: Psychedelics, Psilocybin, Alcohol & Nicotine | Melissa Herman | 170

14 Aug 2024
1h 15m
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Epigenetics, Chromatin Plasticity & the Neural Basis of Memory | Giulia Santoni | 169

09 Aug 2024
1h 23m
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Sleep: Neural Circuits, Orexin/Hypocretin, Hypothalamus, Neuromodulators, Stress & Cortisol, Sleep Drugs & Ultrasound Technology | Luis de Lecea | 168

05 Aug 2024
1h 39m
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Plant Chemistry & the Chemical Basis of Marijuana Aroma | Iain Oswald | 167

26 Jul 2024
51m
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History of Diet & Food, Population Size & Social Stability, Psychological Pandemics, Physical & Mental Health in Civilization Cycles | Rudyard Lynch | 193

19 Jul 2024
2h 9m
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Evolution: Natural Selection, Genetic Drift, Origin of Life, Cellular Complexity, Epigenetics | Michael Lynch | 166

14 Jul 2024
1h 29m
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PUFAs in Brain Health & Disease, Dietary Fats, Brain Lipids, Nutrition | Richard Bazinet | 165

10 Jul 2024
1h 41m
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Seed Oils, Chronic Disease, Diet & Religious Cults, Mainstream Medicine vs. Independent Research | Tucker Goodrich | 192

30 Jun 2024
1h 48m
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Dopamine, Reward, Motivation, Lateral Hypothalamus, Feeding Behavior & Eating Disorders | Melissa Sharpe | 164

26 Jun 2024
1h 8m
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Anesthesia, Placebo Effects, Consciousness, Subjectivity, MDMA, Ketamine, Opioids, Psychedelics | Boris Heifets | 163

22 Jun 2024
1h 44m
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Drugs, Addiction & Neuroplasticity: Psychedelics, MDMA, Opioids, Cocaine, Amphetamine (Adderall), Nicotine, Marijuana & Alcohol | Robert Malenka | 162

16 Jun 2024
1h 34m
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GLP-1, Weight Loss Drugs, Ozempic, Obesity, NMDA Receptors, Metabolism & Brain Health | Christoffer Clemmensen | 161

12 Jun 2024
1h 32m
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Diet, Hunting, Culture and Evolution of Paleolithic Humans & Hunter Gatherers | Eugene Morin | 160

01 Jun 2024
1h 24m
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Neuroscience of Social Behavior, Pain, Empathy, Emotion, Brain Mechanisms of MDMA | Monique Smith | 159

23 May 2024
1h 26m
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Ketosis & Ketogenic Diet: Brain & Mental Health, Metabolism, Diet & Exercise, Cancer, Diabetes | Dominic D'Agostino | 158

16 May 2024
1h 41m
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Preventative Medicine & Lies Taught in Medical Schools | Robert Lufkin | 157

09 May 2024
1h 45m
Page 8

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