Nick Jikomes · Health

Mind & Matter

Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists & thinkers alive today about how your mind-body reacts to what you feed it. The weekly M&M podcast features conversations with the most interesting scientists, thinkers, and technology entrepreneurs alive today. Not medical advice. At M&M, we are interested in trying to figure out how things work, not affirming our existing beliefs. We prefer consulting primary rather than secondary sources and independent rather than institutional voices. If we encounter uncomfortable truths or the evidence suggests unfashionable ideas may be valid, so be it. As the host, my aim is to help you better understand how the body & mind work by curating & synthesizing information in a way that yields science-based insights that you can choose to use or disregard in your own life. Taking ownership of your health starts with taking ownership of your information diet. I am motivated to connect the dots and distill general principles from what I learn, preferring to ask questions and play devil’s advocate to debating or incessantly pushing my own viewpoint. My beliefs: Taking ownership of your health starts with taking ownership of your information diet . All knowledge is provisional and we must work hard to prevent ourselves from becoming attached to our favorite ideas & preferred conclusions. Wisdom comes from an iterative, trial-and-error process of learning and unlearning. Letting go of pre-conceived notions can be painful, but pain is information. Sometimes modern discoveries teach us we must unlearn received wisdom. Other times, modern information overload & historical chauvinism cause us to forget ancient wisdom which stills applies. The framework for learning that I embody is inspired by three Ancient Greek maxims inscribed in the Temple of Apollo at Delphi: “Γνῶθι σεαυτόν” ( Know thyself ) “Μηδὲν ἄγαν” ( Nothing in excess) “Ἐγγύα πάρα δ Ἄτα” ( Certainty brings insanity)

Episodes

Psychology of Stress, Resilience, Emotion & Child Development | Stephen Sideroff | 156

03 May 2024

1h 39m

Cell Biology of Aging, Mitochondria, Metabolism, Autophagy & Stress | Andrew Dillin | 155

29 Apr 2024

1h 39m

Evolution & Genetics of Human Diet, Disease Risk, Skin Color & Origins of Modern Europeans | Eske Willerslev | 154

24 Apr 2024

1h 52m

Diet, Nutrition, Metabolic Psychiatry, Brain & Mental Health | Georgia Ede | 153

19 Apr 2024

1h 51m

Plant Chemistry, Cannabinoids, Cannabis Terpenes & the Entourage Effect | Ryan Vandrey | 152

12 Apr 2024

1h 30m

Aging, mTOR, Sirtuins, Rapamycin, Metformin, the Truth of Resveratrol & Longevity Supplements, David Sinclair & Anti-Aging Myths | Matt Kaeberlein | 151

07 Apr 2024

2h 28m

AI processed

The podcast explores the science of aging, examining factors influencing longevity across species and within individuals. Matt Kaeberlein, CEO of OptiSpan, discusses the evolutionary perspective on aging, highlighting the roles of body size, metabolic rate, and reproductive viability. He notes the mysteries surrounding...

Visual System, Visual Impairments & Cures, Amblyopia, Neuroplasticity, Critical Periods & Metaplasticity, Ketamine & Psychedelics | Mark Bear | 150

03 Apr 2024

1h 16m

DNA & RNA Biology, mRNA Vaccines, Vaccine Contamination & Side Effects, Spike Protein, Ivermectin, Hop Latent Viroid | Kevin McKernan | 149

30 Mar 2024

1h 50m

Dietary Protein, Muscle Growth, Resistance Training, Amino Acids, Plant vs. Animal Protein Sources, Anabolic Growth | Luc van Loon | 148

27 Mar 2024

1h 22m

Ketamine: Opioid System, Sex Differences, S- vs. R- Isomers, Depression & Ultrasound Imaging Technology | Tommaso Di Ianni | 147

22 Mar 2024

1h 21m

Photobiology, Sunlight, Firelight, Incandescent Bulbs vs. LEDs, Mitochondria, Melatonin, Sunscreen & the Optics of the Body | Scott Zimmerman | 146

19 Mar 2024

1h 17m

Epigenetics, Hormones, Endocrine Disruptors, Microplastics, Xenoestrogens, Obesity, Inheritance of Acquired Characteristics | Bruce Blumberg | 145

14 Mar 2024

1h 31m

Inflammation, Innate Immunity, Allergies & Allergens, Immune System Evolution, Fasting & Metabolism | Clare Bryant | 144

10 Mar 2024

1h 32m

Gut-Brain Communication, Vagus Nerve, Fats & Sugars, Food Addiction, Gut Hormones & Weight Loss Drugs | Will de Lartigue | 143

05 Mar 2024

1h 27m

Endogenous DMT in the Mammalian Brain | Nicolas Glynos | 142

29 Feb 2024

1h 36m

Evolution, Language, Domestication, Symbolic Cognition, AI & Large Language Models | Terrence Deacon | 141

24 Feb 2024

2h 14m

Obesogens, Oxidative Stress, Dietary Sugars & Fats, Statins, Diabetes & Causes of Metabolic Dysfunction & Chronic Disease | Robert Lustig | 140

17 Feb 2024

1h 59m

Metabolic Switching, Fasting, Ketosis, Neuroplasticity, Diet & Neurodegenerative Disease | Mark Mattson | 139

14 Feb 2024

1h 41m

Evolution & Animal Development: How Nature Builds & Changes Bodies | Sean B. Carroll | 138

09 Feb 2024

1h 53m

DMT, Serotonin, Inflammation, Psychedelics, and Past, Present & Future of Psychedelic Medicine | David & Charles Nichols | 137

06 Feb 2024

1h 37m

Page 9

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