Send us a text

About the guest: Robert Malenka, MD, PhD is psychiatrist & neuroscientist. He has spent most of his career at Stanford University, where his lab studies synaptic plasticity, mechanisms of drug action in the brain, and the neural basis of behavior.

Episode summary: Nick and Dr. Malenka discuss: mechanisms of synaptic plasticity in the brain, such as LTP & LTD; addiction & the dopamine reward circuitry of the brain; psychoactive drugs ranging from stimulants (cocaine, nicotine, amphetamines) to opioids (fentanyl), psychedelics, MDMA, THC, and alcohol; and more.

Related episodes:

Support the show

All episodes, show notes, transcripts, and more at the M&M Substack

Affiliates:

KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime)
Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off
Readwise: Organize and share what you read. 60 days FREE through link
SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount.
MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off

For all the ways you can support my efforts

Drugs, Addiction & Neuroplasticity: Psychedelics, MDMA, Opioids, Cocaine, Amphetamine (Adderall), Nicotine, Marijuana & Alcohol | Robert Malenka | 162

Mind & Matter

Drugs, Addiction & Neuroplasticity: Psychedelics, MDMA, Opioids, Cocaine, Amphetamine (Adderall), Nicotine, Marijuana & Alcohol | Robert Malenka | 162