

The Human Upgrade: Biohacking for Longevity & Performance
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio , he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
Episodes


How to Get and Stay Sober in 2026 (The Biohacker’s Guide) | Luke Storey : 1386
In this episode of The Human Upgrade, Dave Asprey interviews Luke Storey about addiction, recovery, and the use of psychedelics for healing. Luke shares his personal journey from addiction to sobriety, emphasizing the role of spirituality and community in his recovery. They discuss the increasing prevalence of addictio...

What it takes to be “Young Forever!” | Mark Hyman : 1385
In this episode of The Human Upgrade, Dave Asprey interviews Dr. Mark Hyman about his new book, "Young Forever," which explores the science of longevity and how to reverse biological aging. They discuss the hallmarks of aging, including deregulated nutrient sensing, insulin signaling, mTOR, AMPK, and sirtuins, and how ...

I Tried $50 Brain Boosting Powder : 1384

Biohacking News Weekly Update : 1383

The Science of Erotic Altered States | Biohacking Sex : 1382

Biohacking Fertility for Men and Women at Any Age : 1381

Your Brain Has A Sleep Switch (Do THIS To Turn It On) : 1380

The One Thing Everyone Thinks They Can’t Afford… Until They Try It : 1379

How To Sculpt a Perfect Jawline WITHOUT Surgery : 1378
In this episode of The Human Upgrade, Dave Asprey interviews the creator of Jawsercise, discussing the benefits of jaw exercise for improving facial structure, neurological strength, and overall health. The guest shares his personal experience with jaw injuries and how it led to the development of the Jawsercise device...

I Tried At-Home Ultrasound for My Brain : 1377
In this episode of "The Human Upgrade," Dave Asprey interviews Jon Hacker, CEO of Zenbud, about the use of ultrasound technology to stimulate the vagus nerve for stress reduction, anxiety relief, and overall nervous system regulation. They discuss the science behind vagus nerve stimulation, contrasting ultrasound with ...

What If You Stop Eating For 72 Hours? : 1375

The Real Reason Your Face Is Aging So Fast : 1376

Feel 70 Percent Better… With Grapes? | Biohacking Tools : 1374

The Machine That Flicks on Your Brain in 30 Seconds | Biohacker Tools : 1373

How I Lost 100 Pounds By Drinking Butter Coffee : 1371
Dave Asprey shares his personal journey of losing 100 pounds and improving his health through biohacking and understanding the role of fat, nutrient-dense foods, intermittent fasting, and minimizing toxins. He recounts his experience with yak butter tea in Tibet, which led him to develop Bulletproof Coffee, and emphasi...

Get a Full Body Workout in 10 Minutes by Doing NOTHING | Biohacks : 1372
In this episode of The Human Upgrade, Dave Asprey interviews Dr. Tommy Rhee about the benefits of whole body vibration, specifically using Power Plates. They discuss how Power Plates can improve circulation through nitric oxide release, enhance lymphatic drainage, and offer neurological benefits, including improved bal...

How to Stop Brain Fog After Anesthesia | Biohacker Tips : 1370

Why Breathwork Feels Like a Euphoric Drug | Biohacker Tips : 1369

Dead Water Is Making You Sick! (Biohacking Bonus Episode) : 1368
In this monologue podcast, Dave Asprey discusses the importance of mineralized water for optimal hydration and overall health, contrasting it with "dead water" lacking essential minerals, which he argues is prevalent in both tap and bottled water. He debunks the myth of needing eight glasses of water daily, attributing...
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