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Andreessen Horowitz · Technology

The a16z Show

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

Episodes

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Marc Andreessen and Amjad Masad: English As the New Programming Language

23 Oct 2025
1h 11m
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In this episode of the a16z Podcast, Erik Torenberg and Marc Andreessen interview Amjad Masad, CEO and founder of Replit, about the evolution of coding through AI agents. They discuss how AI is making programming more accessible by abstracting away the complexities of syntax, allowing users to describe their ideas in n...

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Why Creativity Will Matter More Than Code

22 Oct 2025
1h 25m
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Kevin Rose and Anish Acharya discuss the resurgence of consumer technology driven by AI, touching on the early days of the internet and the invention of the like button. They explore the shift in consumer behavior, the potential for AI in companionship and emotional support, and the evolving landscape of product buildi...

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How Kong Was Born: APIs, Hustle, and the Future of AI Infrastructure

21 Oct 2025
37m
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The podcast features an interview with Augusto Aghi Marietti, CEO and co-founder of Kong, and Martin Casado, a16z general partner. They discuss Aghi's journey from starting in a Milan garage to building Kong, a leading API platform. The conversation covers the company's early struggles, including living on minimal fund...

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Reid Hoffman on AI, Consciousness, and the Future of Humanity

20 Oct 2025
53m
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In this episode of the A16z Podcast, Reid Hoffman and Alex Rampell join the host to discuss the impact of AI on work and humanity. They explore AI's potential beyond obvious productivity gains, highlighting blind spots in Silicon Valley's approach, such as overlooking the intersection of AI with fields like biology and...

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Marc Andreessen on the State of Film and Hollywood

17 Oct 2025
1h 7m
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In this episode of "Monitoring the Situation," Marc Andreessen joins Katherine Boyle and Erik Torenberg to discuss the state of Hollywood and the film industry. They explore the cultural impact of movies, the shift in filmmaking since 2019, and the influence of streaming services on financial incentives and content cre...

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Keith Rabois: Israel, OpenAI, Opendoor, and DOGE

16 Oct 2025
49m
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This podcast episode features Keith Rabois and Alex Rampell discussing a wide range of topics, including the emerging new Middle East and its implications for US politics, particularly concerning Trump's potential second term. They explore the concept of sovereign AI and its role in redefining national competitiveness,...

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Ben Horowitz and Ali Ghodsi: How to Run a Billion-Dollar Business

15 Oct 2025
1h 4m
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In this episode of Boss Talk, Databricks CEO Ali Ghodsi, along with Ben Horowitz and Sarah Wang, discuss the company's journey, including a near-crisis in 2016 and the pivotal Microsoft deal. They delve into Ali's transition from academia to CEO, highlighting the importance of continuous learning, hiring exceptional ta...

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Is AI Slowing Down? Nathan Labenz Says We're Asking the Wrong Question

14 Oct 2025
1h 31m
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In this episode of the a16z Podcast, Nathan Labenz of the Cognitive Revolution joins the host to discuss the question of whether AI innovation is slowing down. They address arguments suggesting a slowdown, such as students using AI for laziness and claims that GPT-5 isn't a significant improvement over GPT-4. Nathan ar...

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Columbia CS Professor: Why LLMs Can’t Discover New Science

13 Oct 2025
50m
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In this episode of the a16z Podcast, Vishal Misra and a16z's Martin Casado discuss large language models (LLMs), retrieval augmentation generation (RAG), and formal models that explain the capabilities and limitations of LLMs. Vishal shares his background in networking and how his attempt to fix a cricket stats page le...

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Monitoring the Situation #3: Who Is Nick Land?

12 Oct 2025
52m
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In this episode of "Monitoring the Situation," Guido Appenzeller hosts a discussion on the future of energy with a16z general partners Katherine Boyle and Erin Price-Wright, and Base Power CEO Zach Dell, exploring affordable local power generation, data center buildout misconceptions, and fixing the US electricity grid...

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Sam Altman on Sora, Energy, and Building an AI Empire

08 Oct 2025
48m
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In this episode of the a16z Podcast, Sam Altman, CEO of OpenAI, discusses OpenAI's vision to create a personal AI subscription service, supported by massive infrastructure and cutting-edge research. Altman reflects on the rapid progress in AI, including the development of models capable of scientific discovery, and the...

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How to Build a Real Estate Marketplace - Kaz Nejatian, Opendoor CEO

07 Oct 2025
55m
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In this episode of the a16z Podcast, host interviews a16z general partner, Alex Rampell, and Opendoor's CEO, Kaz Nejatian, about fixing the painful, opaque, and inefficient real estate market. They discuss why real estate has resisted disruption, how a marketplace model could break the real estate agency cartel, and Op...

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Can the US Beat China’s Engineering State?

06 Oct 2025
1h 3m
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In this episode of the a16z Podcast, Guido Appenzeller hosts Dan Wang, author of "Breakneck," and Steven Sinofsky, board member at a16z and former Microsoft executive, to discuss the competition between the U.S. and China. The conversation explores the contrasting approaches of the U.S. as a lawyer-led society and Chin...

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Monitoring the Situation #2: Alana Newhouse

05 Oct 2025
58m
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In this episode of Monitoring the Situation, Alana Newhouse, founder and editor-in-chief of Tablet Magazine, joins the hosts to discuss the evolving landscape of American media. The conversation revolves around the shift from legacy media to independent media, the impact of subscription-based models, and the changing r...

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Software is Eating Labor

03 Oct 2025
26m
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Alex Rampell from a16z discusses how software is evolving to "eat labor," moving beyond simply digitizing filing cabinets to performing entire jobs end-to-end. He contrasts the $300 billion SaaS market with the $13 trillion U.S. labor market, arguing that the real opportunity lies in outcome-based software that directl...

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The Ben & Marc Show: China Has Scale. Can America Catch Up?

02 Oct 2025
57m
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The Ben and Marc Show features Brian Schimpf, CEO of Anduril, and Chris Power, CEO of Hadrian, discussing the U.S.'s manufacturing challenges in the context of competition with China. They emphasize that the U.S. has fallen behind in manufacturing due to outsourcing, lack of skilled labor, and insufficient strategic pl...

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Cheeky Pint: Marc Andreessen, John Collison & Charlie Songhurst on Tech’s Big Questions

01 Oct 2025
2h 9m
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In this episode of Cheeky Pint, John Collison hosts Marc Andreessen and Charlie Songhurst for a discussion about bubbles, downturns, and risk-taking in Silicon Valley. They explore the challenges of identifying bubbles in real-time, the impact of economic downturns on entrepreneurial ecosystems, and the high-trust cult...

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Building an AI Physicist: ChatGPT Co-Creator’s Next Venture

30 Sep 2025
54m
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In this episode of the a16z Podcast, Anjney Midha interviews Liam Fedus and Ekin Dogus Cubuk, co-founders of Periodic Labs, about their work on building experiment-in-the-loop AI for physics and chemistry. They discuss the importance of real-world reward functions, how mid-training and high-compute reinforcement learni...

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Meta CMO: How Advertising Works Under the Hood

29 Sep 2025
1h 2m
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The a16z Podcast features a discussion with Alex Schultz, CMO at Meta, and Antonio Garcia-Martinez, Director of Ads at Coinbase, centered around Schultz's book "Click Here," which defends online advertising. The conversation explores the positive aspects of online ads, addressing common critiques related to data privac...

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The Common Thread of All Technology: Monitoring the Situation, Ep.1

27 Sep 2025
1h 0m
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In this podcast episode, Katherine Boyle and the host engage with Eddie Lazzarin from a16z crypto team to discuss the connections between consumer trends, crypto, and American dynamism. They explore how gaming influences defense technology and how decentralization mirrors federalism, touching on AI, ADHD diagnoses, the...

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