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Andreessen Horowitz · Technology

The a16z Show

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

Episodes

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Ben Horowitz & Marc Andreessen: Why Silicon Valley Turned Against Defense (And How We’re Fixing It)

19 Nov 2025
1h 16m
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The a16z Podcast episode features a discussion on "American Dynamism," a concept focused on rebuilding America's industrial base through investments in areas like defense tech, energy, manufacturing, and infrastructure. Marc Andreessen, Ben Horowitz, Katherine Boyle, and David Ulevitch explore the historical disconnect...

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Emmett Shear on Building AI That Actually Cares: Beyond Control and Steering

17 Nov 2025
1h 10m
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The podcast features Emmett Shear, co-founder of Twitch and now working on AI alignment at Softmax, along with Seb Krier from Google DeepMind, discussing AI alignment with host Erik Torenberg. Emmett introduces the concept of "organic alignment," emphasizing it as an ongoing process of learning and adaptation rather th...

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Can America Win The AI Biotech Race Against China? | Lada Nuzhna & Elliot Hershberg

14 Nov 2025
1h 2m
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In this a16z Podcast episode, Lada Nuzhna and Elliot Hershberg discuss the biotech industry's paradox: exploding technology amid collapsing business. They explore challenges like increasing regulation, high drug approval costs, and the rise of Chinese biotech. The conversation covers potential solutions such as AI in d...

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The Frontier of Spatial Intelligence with Fei-Fei Li

13 Nov 2025
44m
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In this episode of the a16z Podcast, Erik Torenberg replays a conversation with Fei-Fei Li and Justin Johnson, co-founders of World Labs, and a16z general partner Martin Casado, discussing spatial intelligence and its importance for achieving true AI. They explore the evolution of AI, from ImageNet to generative models...

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Rocket Companies CEO: Here’s How to Fix the Housing Crisis

12 Nov 2025
55m
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The podcast features Erik Torenberg, Alex Rampell, and Varun Krishna discussing the challenges and potential solutions to the decreasing rate of homeownership among younger people. They attribute this issue to asset price inflation, the increasing difficulty of building new homes due to regulations and NIMBYism, and cu...

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Grant Lee: Building Gamma’s AI Presentation Company to 100 Million Users

11 Nov 2025
53m
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In this episode of the a16z Podcast, Grant Lee, co-founder and CEO of Gamma, discusses the journey of building Gamma into a successful AI-driven presentation tool. He recounts early fundraising challenges, including a brutal pitch rejection, and emphasizes the importance of product-led growth and focusing on word-of-mo...

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Michael Truell: How Cursor Builds at the Speed of AI

10 Nov 2025
27m
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Michael Truell, CEO of Cursor, discusses the company's origins, pivoting from a 3D company to focusing on AI coding tools, and the strategic decisions that fueled its rapid growth. Truell emphasizes the importance of focus, initially building a better product within the VS Code ecosystem before expanding into multi-pro...

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a16z's State of Crypto: The $4 Trillion Milestone and What's Next'

09 Nov 2025
1h 38m
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In this episode of the Web3 with a16z podcast, Robert Hackett hosts Daren Matsuoka and Eddy Lazzarin from a16z Crypto to discuss the findings of their 2025 State of Crypto Report. The discussion covers crypto's mainstream adoption, the increasing importance of stablecoins, and institutional interest in crypto. They exp...

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Amjad Masad & Adam D’Angelo: How Far Are We From AGI?

07 Nov 2025
1h 2m
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This podcast features a discussion between Adam D'Angelo, Amjad Masad, and a host about the current state and future of AI, particularly LLMs. Adam expresses optimism about the rapid progress in AI, while Amjad is more cautious, emphasizing the brute force nature of current AI development and its potential negative imp...

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Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease

06 Nov 2025
45m
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In this episode of the a16z Podcast, Priscilla Chan and Mark Zuckerberg discuss the Chan Zuckerberg Initiative's (CZI) mission to cure, prevent, and manage all diseases by the end of the century through basic science and tool development. They share insights into their focus on building shared tools and datasets, the C...

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Seeing The Future from AI Companions to Personal Software

05 Nov 2025
50m
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In this episode of the a16z Podcast, Eugenia Kuyda, the founder of Replika and Wabi, discusses the evolution of AI interfaces and her vision for the future of personal software. Kuyda reflects on her early work in AI, the limitations of current chatbot interfaces, and the potential for mini-apps to revolutionize how pe...

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ElevenLabs CEO: Why Voice is the Next AI Interface

05 Nov 2025
31m
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In this interview, Mati Staniszewski, co-founder and CEO of ElevenLabs, discusses the company's approach to maintaining speed and quality in product development, balancing research with product launches, and building a global, distributed team. Mati shares insights on fostering collaboration with the creative industry,...

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David Sacks: AI, Crypto, China, Dems, and SF

03 Nov 2025
1h 16m
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In this a16z Podcast episode, David Sacks, Marc Andreessen, and Ben Horowitz discuss the global race for technological and economic leadership, focusing on AI and crypto. They analyze the Trump administration's policy approaches to AI and crypto, contrasting them with those of the Biden administration and Europe. The c...

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Why Speed, Not Size, Will Define the Next War

01 Nov 2025
39m
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In this episode of the a16z Podcast, host Erik Torenberg interviews Horacio Rozanski, CEO of Booz Allen Hamilton, and Gary Steele, CEO of Shield AI, about the reshaping of America's defense strategy through technology and partnerships. The discussion covers America's readiness to defend Taiwan, the importance of autono...

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Beyond Chatbots: Marc Andreessen and Ben Horowitz on AI's Future

31 Oct 2025
38m
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In this a16z podcast episode, Marc Andreessen and Ben Horowitz discuss the current state of AI, addressing questions about the limitations of LLMs in creative genius and original thought, and comparing AI capabilities to human intelligence. They explore whether AI can truly achieve conceptual breakthroughs or if it pri...

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"Is there an AI bubble?” Gavin Baker and David George

30 Oct 2025
31m
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David George from a16z and Gavin Baker from Atreides Management discuss the state of AI, addressing whether it's in a bubble by comparing it to the internet bubble of 2000, noting the key difference of "dark fiber" versus the current high utilization of GPUs. They explore AI's impact on capital allocation, infrastructu...

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Building the Real-World Infrastructure for AI, with Google, Cisco & a16z

29 Oct 2025
32m
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The podcast features a discussion with Amin Vahdat from Google, Jeetu Patel from Cisco, and Raghu Raghuram from a16z, focusing on the infrastructure build-out required to support large-scale AI. They explore the unprecedented scale of the current AI boom, comparing it to the internet's early days but noting it's potent...

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Google DeepMind Developers: How Nano Banana Was Made

28 Oct 2025
54m
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In this episode of the A16Z podcast, Oliver Wang and Nicole Brichtova from Google DeepMind discuss Gemini 2.5 image, also known as Nano Banana. They delve into the model's architecture, its integration of image generation and editing within Gemini's multimodal framework, and the challenges of achieving character consis...

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Raghu Raghuram: AI, Robotics, and the Rebirth of Infrastructure

27 Oct 2025
30m
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In this episode of the a16z Podcast, a16z co-founder Ben Horowitz and general partners Martin Casado and David George interview Raghu Raghuram, a16z's newest managing director and general partner, about building and scaling enterprise software across multiple platform shifts, drawing lessons from Netscape and VMware. T...

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Marc Andreessen: How Movies Explain America

24 Oct 2025
1h 15m
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In this episode of Monitoring the Situation, Marc Andreessen joins Katherine Boyle and another speaker to discuss films that capture America's turning points. They analyze "Once Upon a Time in Hollywood," exploring its depiction of 1969 Los Angeles and the Manson murders as a cultural pivot. They discuss Tarantino's ap...

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