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Mario Gabriele · Business

The Generalist

“The future is already here. It’s just not evenly distributed.” The Generalist Podcast brings you weekly conversations with the people who live in these pockets of the future – visionary founders, prescient investors, and original thinkers. Each episode is designed to introduce you to new ideas, technologies, and markets and help you prepare for the world of tomorrow.

Episodes

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A portrait of eight billion people

03 Nov 2026
1h 10m
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Simile leverages generative AI to build foundation models of human behavior, enabling the simulation of individuals and populations with over 85% accuracy. By creating digital twins from behavioral and interview data, the company allows enterprises to test strategies, products, and policies in virtual environments befo...

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Pete Florence: When Robots Improvise

20 Oct 2026
1h 5m
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Physical intelligence represents the next frontier in AI, moving beyond digital tasks to enable robots to manipulate the physical world with human-like dexterity. Pete Florence, co-founder and CEO of Generalist, highlights the breakthrough capabilities of the Gen 1.5 foundation model, which demonstrates one-shot and fe...

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Jaan Tallinn would like us to survive

08 Oct 2026
1h 7m
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Advanced AI development currently follows an inherently dangerous trajectory, driven by economic incentives that prioritize agentic, self-sustainable systems over safety. Jaan Tallinn, a veteran AI safety advocate and early investor in DeepMind and Anthropic, argues that the recent OpenAI/Hugging Face incident demonstr...

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Periodic Labs: A chatbot walks into a laboratory

29 Sep 2026
59m
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Periodic Labs aims to build "synthesis superintelligence" by bridging the gap between digital AI reasoning and physical scientific experimentation. While LLMs excel at coding and mathematics due to instantly verifiable rewards and complete context, scientific discovery requires navigating uncertainty and physical const...

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An Ex-SpaceX Engineer on Elon Musk, Starship, and Building a $1B-Valued Startup (Scott Morton, Founder & CEO of Revel)

08 Sep 2026
57m
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Industrial control software has remained stagnant since the 1980s, creating a critical bottleneck for companies building complex hardware like rockets and nuclear reactors. Revel addresses this by providing a modern software platform designed to replace outdated, inefficient legacy systems. Founded by SpaceX veteran Sc...

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38x in Ten Months: Inside One of Fintech’s Fastest-Growing Infrastructure Companies (Farooq Malik, CEO of Rain)

18 Aug 2026
1h 15m
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AI Got Good at Language. Now It’s Learning the Language of Life. (Eric Nguyen, Co-Founder and CEO of Radical Numerics)

04 Aug 2026
1h 22m
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The Token Budget Problem Nobody Is Talking About (Matan Grinberg, Co-Founder & CEO of Factory)

30 Jun 2026
1h 16m
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Own or Be Owned: Why Every Company Needs Its Own AI Model (Yash Patil, Co-Founder & CEO of Applied Compute)

23 Jun 2026
1h 8m
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Owning proprietary intelligence is becoming an existential necessity for enterprises as reliance on general-purpose frontier models creates significant cost inefficiencies and data security risks. Yash Patil, founder of Applied Compute and former OpenAI researcher, argues that companies should leverage open-weight mode...

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What America Is Missing Between Sanctions and Nuclear War (Bryon Hargis, Co-Founder & CEO of Castelion)

02 Jun 2026
1h 16m
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“Our Goal Is to Build an Electrical Engineer.” (Davide Asnaghi, Co-Founder & CEO of Diode)

19 May 2026
1h 12m
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Diode aims to revitalize American hardware manufacturing by creating an "AWS for electronics," enabling rapid prototyping and production of circuit boards. By integrating large language models into the design process, the company removes traditional bottlenecks, allowing hardware startups to iterate with the speed of s...

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Investing Like A Mystic: How Cyan Banister Finds Outliers (Co-Founder of Long Journey Ventures)

05 May 2026
1h 13m
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The Future Of Drug Discovery Is 4 Billion Years Old (Viswa Colluru, Founder & CEO at Enveda)

21 Apr 2026
1h 22m
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How a 20-Person Startup Won Gold at the Math Olympiad—Tying With OpenAI & DeepMind (Tudor Achim, CEO of Harmonic)

14 Apr 2026
1h 4m
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30% Of Network Engineers Are Retiring. What Happens Next? (Anil Varanasi, Co-Founder & CEO of Meter)

07 Apr 2026
1h 10m
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Why One Superintelligence Is More Dangerous Than a Thousand (Vincent Weisser, CEO & Co-Founder of Prime Intellect)

24 Mar 2026
1h 19m
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Why Robots Still Struggle With Simple Tasks (And What Might Finally Change That) | Karol Hausman, Co-Founder & CEO of Physical Intelligence

17 Mar 2026
1h 14m
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Physical intelligence represents the next frontier in robotics, shifting from rigid, pre-programmed machines to generalist models capable of navigating diverse environments. By integrating large language models with robotic motion, these systems leverage vast internet-based knowledge to generalize across tasks, moving ...

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America’s Electric Power Grid Is Broken. This Startup Is Trying to Fix It. (Zach Dell, co-founder & CEO of Base)

10 Mar 2026
1h 11m
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Everyone Is Betting on Bigger LLMs. She's Betting They're Fundamentally Wrong. (Eve Bodnia, Founder & CEO of Logical Intelligence)

24 Feb 2026
1h 7m
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How Bolt Survived An 85% Revenue Crash And Became Europe's Ride-Hailing Champion (Markus Villig, Founder & CEO)

19 Feb 2026
1h 20m
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Markus Villig, CEO of Bolt, discusses the company's origins, culture, and strategies for competing in the transportation and logistics market. Villig emphasizes Bolt's underdog mentality, rooted in Estonia's history and culture, and its focus on operational excellence and frugality. He recounts Bolt's pivot to food del...

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