The Generalist

Nothing’s Carl Pei on Building a $1B Smartphone Company, Why He Left OnePlus After 10 Days of Retirement, and Why He Thinks About Death Every Week

Why Being a Generalist VC Is a Competitive Advantage (Aydin Senkut, Founder & Managing Partner at Felicis Ventures)

Aydin Senkut of Felicis Ventures shares his journey from Istanbul to Silicon Valley, detailing Felicis's evolution from a solo operation to a $900 million fund. Senkut emphasizes the importance of international perspective and a generalist investment approach, contrasting it with the specialist model. He recounts lesso...

Joey Krug on Prediction Markets, Crypto Treasuries & the Next Era of On-Chain Finance (Partner at Founders Fund)

In this episode of The Generalist, Mario Gabriele interviews Joey Krug, a partner at Founders Fund, about his history with prediction markets, crypto treasury movements, and the state of the crypto markets. Krug discusses his early interest in betting and modeling, which led to his involvement in crypto and the creatio...

How a Solo Founder is Reshaping Global Finance (Parth Garg, CEO of Aspora)

The $170M Experiment to Build a Private City in Honduras | Erick Brimen (Founder and CEO of Próspera)

Why Psychedelics Might Be the Breakthrough That PTSD Patients Need | Kevin Ryan (The Godfather of NYC Tech)

In The Generalist podcast, Mario Gabriele interviews Kevin Ryan, a serial entrepreneur and founder of AlleyCorp, about his experiences in tech, venture capital, and company incubation. They discuss the importance of a great team and idea for a successful company, the challenges of incubating companies, and the changing...

The Trillion-Dollar AI Hardware Opportunity | Navin Chaddha (Managing Partner, Mayfield)

Biological Time Travel: How Cryopreservation Could Transform Medicine | Laura Deming (CEO & co-founder of Until)

"This feels like 1996": Why a16z's Martin Casado believes the AI boom still has years to run (General Partner)

In The Generalist podcast, Mario Gabriele interviews Martin Casado, a general partner at Andreessen Horowitz, about his journey from game development to venture capital, focusing on his investment style, which prioritizes market analysis over individual company assessment. Casado draws parallels between the current AI ...

How to be Agentic in the Age of AI | Cate Hall (CEO of Astera)

Maintaining Human Intelligence in the AI Era | David Krakauer (President of the Santa Fe Institute)

Building Beautiful Homes with Robots: The Future of Construction | Salar al Khafaji (CEO and Founder of Monumental)

What Makes Something Alive? Assembly Theory and the Origins of Life | Sara Walker (Theoretical Physicist)

Reviving Forgotten Technologies: How Airships, Supersonic Flight, and Geothermal Energy Could Transform Our World | Eli Dourado (Head of Strategic Investments at Astera Institute)

Inside General Catalyst’s $1B+ Bet on Fixing Healthcare | Hemant Taneja (CEO and Managing Partner)

The Future of Crypto: Stablecoins, AI Integration, and the Path to Mass Adoption | Jesse Walden (Founder and Managing Partner at Variant)

The Evolution of AI Agents: Navigating the “Fog of AI” in Rapidly Changing Foundations | Stanislas Polu and Harrison Chase

The Decade of Data with Tomasz Tunguz

Why the Real Computer Revolution Never Happened | Alan Kay & Anjan Katta

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