The Peter Attia Drive - Private Subscriber Feed (🔓 for Vijay Khakhria)

#411 ‒ AMA #90: Strong convictions, loosely held: how Peter’s views on fasting, keto, metformin, rapamycin, whole-body MRI, and exercise have changed

Reflecting on 400 episodes of "The Drive," Peter Attia reevaluates long-held health positions by prioritizing clinical data and principles over rigid interventions. Metabolic health remains foundational, though the focus has shifted from specific dietary dogmas like ketogenic diets or extended fasting toward sustainabl...

#410 ‒ The biology of pregnancy: physiologic adaptation, gestational diabetes, preeclampsia, childbirth, and long-term maternal health | Kathryn Gray, M.D., Ph.D.

#409 ‒ Inside modern drug development: the science, economics, and regulatory hurdles behind bringing new medicines to patients | Lloyd Klickstein, M.D., Ph.D.

#408 ‒ AMA #89: Thyroid health: interpreting symptoms, diagnosing and treating dysfunction, and navigating the gray zone

#407 ‒ Preventing cardiovascular and Alzheimer’s disease: lowering LDL early, APOE4, and promising new therapies | Michael Davidson, M.D.

Blood pressure: how to measure, manage, and treat high blood pressure (AMA #48 rebroadcast)

#406 ‒ Migraine, cluster headache, and tension headache: symptoms, causes, prevention, and treatment | Brian Grosberg, M.D.

#405 ‒ AMA #88: Metabolic liver health: how to assess risk, catch dysfunction early, and prevent or reverse liver disease

#404 ‒ Mental health beyond neurotransmitters: the role of hormones in psychiatry, why symptom reduction isn't enough, and the future of psychedelic therapies | Linus Abrams, M.D.

#403 ‒ Peptides: separating scientific promise from marketing hype

#402 ‒ NMR blood analysis: how heart disease risk, insulin resistance, inflammation, and mortality risk can be assessed from a single blood sample | Jim Otvos, Ph.D.

#401 ‒ How curiosity transforms medicine: extraordinary discoveries that changed modern healthcare

#400 ‒ AMA #87: Environmental pollution and longevity: air pollution, noise, light, EMFs, and practical strategies to mitigate health risks

#399 ‒ The evolution of Alzheimer's disease and dementia care: how early detection, personalized treatment, new therapies, and a multimodal approach are changing the landscape | Gayatri Devi, M.D.

Building strength and muscle mass: how to optimize training, nutrition, and more for longevity (AMA #71 rebroadcast)

#398 ‒ AMA #86: GLP-1 RAs and muscle loss: new data, better questions, and how to preserve muscle during weight loss

GLP-1 receptor agonists like semaglutide and terzepatide induce significant weight loss, yet the associated reduction in lean mass often stems from rapid weight reduction rather than direct muscle wasting. DEXA scans frequently misinterpret changes in intramuscular adipose tissue and hydration as muscle loss, failing t...

#397 ‒ Endometriosis and adenomyosis: diagnosis, fertility, reproductive aging, and emerging treatments | Renato Tomioka, M.D., Ph.D.

#396 ‒ Breast cancer screening: understanding risk, deciding when to start and how often to screen, and choosing the right imaging strategy

#395 - Brain lipidology: understanding APOE, cholesterol homeostasis, Alzheimer's disease risk, and the effects of lipid-lowering therapies on brain health | Tom Dayspring, M.D.

#394 ‒ Sleep pharmacology: the role of medications in healthy sleep, the promise of emerging therapies, and the evidence for common sleep supplements