This episode of NEJM This Week covers a range of medical research and perspectives. It examines the effectiveness of mucoactive therapies for bronchiectasis, the risks of aspirin use in anticoagulated patients with coronary disease, and the potential of sotatercept for early pulmonary arterial hypertension. The podcast further explores the genetic underpinnings of misdiagnosed common diseases and strategies for managing uncertainty in medical training. Additionally, it presents a case study of systemic amyloidosis and offers perspectives on sickle cell disease, fetal personhood, and the experience of living with a genetic diagnosis, concluding with images in clinical medicine.
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