NEJM This Week — October 16, 2025

This episode of NEJM This Week covers a range of medical research and perspectives. It includes discussions on sentinel lymph node biopsy in cervical cancer, a phase 3 trial for systemic lupus erythematosus, long-term safety and efficacy of gene therapy for adenosine deaminase deficiency, and mass administration of azithromycin to infants for mortality reduction. Additionally, the episode features a review of hair loss in women, a case study of tuberculosis in advanced HIV, and perspectives on vaccines, primary care challenges, digital health for tobacco cessation, infection surveillance, AI in disaster response, Medicare policy, and bearing witness in conflict zones.