This podcast episode provides an in-depth look at Candidemia, a rising global health threat characterized by significant mortality rates and growing incidence, particularly during the COVID-19 pandemic. Infectious diseases specialist Caroline Agnelli discusses the challenges of early diagnosis due to nonspecific symptoms and limitations of current testing methods, stressing the importance of prompt treatment with antifungals and infection source control. The episode also highlights the increasing concern around antifungal resistance, showcasing the evolving landscape of Candida species, and emphasizes the need for ongoing vigilance and adaptive management strategies in combating this severe infection.