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Y Combinator · Business

Y Combinator Startup Podcast

We help founders make something people want. The Y Combinator Podcast is where builders talk about building. From the earliest days of an idea to scaling a company that changes the world, YC partners and founders share real stories, lessons, and tactics from the frontlines.

Episodes

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Building a Brand People Will Care About | Karri Saarinen, Linear CEO

25 Jul 2025
43m
AI processed

In this episode of Design Review, Karri Saarinen, co-founder and CEO of Linear, joins the host to review startup websites, focusing on branding. Karri emphasizes the importance of authenticity and aligning the website's polish with the company's stage, cautioning against creating overly fancy sites too early. He uses L...

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Chelsea Finn: Building Robots That Can Do Anything

22 Jul 2025
44m
AI processed

The podcast features a presentation about developing general-purpose robots with physical intelligence, focusing on the challenges of creating robots that can perform various tasks in different environments. The speaker discusses the importance of scale and diversity in data collection, highlighting the pre-training an...

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Replit CEO Amjad Masad: Coding Agents, Autonomy, and the Future of Work

22 Jul 2025
35m
AI processed

In this episode of The Breakdown, Amjad Masad, founder and CEO of Replit, discusses the evolution of Replit from a coding education tool to an AI-assisted development platform. Masad shares insights on Replit's mission to make programming more accessible, the company's "bet the company" moment on AI agents, and the imp...

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John Jumper: AlphaFold and the Future of Science

15 Jul 2025
27m
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John Jumper discusses his journey into AI for science, emphasizing its potential to accelerate scientific discovery and improve healthcare. He recounts his transition from physics to computational biology and machine learning, driven by a desire to apply his skills to practical problems. Jumper highlights the developme...

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Aravind Srinivas: The Race to Build the AI Browser of the Future

11 Jul 2025
43m
AI processed

In this interview, Aravind Srinivas, the CEO of Perplexity, discusses the company's focus on accuracy and speed in AI search, its upcoming browser Comet, and strategies for competing with tech giants like Google and OpenAI. He shares insights on Perplexity's origins, its initial focus on Twitter search, and the shift t...

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Andrew Ng: Building Faster with AI

10 Jul 2025
43m
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In this Q&A session, Andrew Ng shares insights on building AI startups with a focus on speed and execution. He emphasizes the importance of concrete ideas, rapid engineering through AI coding assistants, and fast user feedback. Ng also highlights the significance of understanding AI technology and encourages everyone t...

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François Chollet: The ARC Prize & How We Get to AGI

03 Jul 2025
34m
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François Chollet discusses the pursuit of Artificial General Intelligence (AGI), highlighting the shift from scaling up pre-training models to test-time adaptation. He argues that true intelligence is the ability to adapt to novel situations, not just memorizing skills. Chollet introduces the Abstraction and Reasoning ...

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Fei-Fei Li: Spatial Intelligence is the Next Frontier in AI

01 Jul 2025
44m
AI processed

In this interview podcast, Dr. Fei-Fei Li, renowned AI expert and entrepreneur, discusses her pioneering work in AI, including the creation of ImageNet and her current focus on spatial intelligence and 3D world modeling with her new company, WorldLabs. She reflects on the evolution of AI, from object recognition to sce...

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Legendary Consumer VC Predicts The Future Of AI Products

27 Jun 2025
35m
AI processed

In this episode of The Main Function, Garry interviews Kirsten Green, co-founder and managing partner of Forerunner Ventures, about the future of consumer AI. They discuss the rapid adoption of AI by consumers, the potential for AI to create deeper, more personalized relationships, and the importance of voice interface...

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Satya Nadella: Microsoft's AI Bets, Hyperscaling, Quantum Computing Breakthroughs

25 Jun 2025
40m
AI processed

In this interview, Satya Nadella, the CEO of Microsoft, discusses the transformative impact of AI across various sectors. Nadella emphasizes Microsoft's role as a platform, product, and partner company in the AI landscape, highlighting the compounding effects of AI built upon previous technological platforms like cloud...

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Sam Altman: The Future of OpenAI, ChatGPT's Origins, and Building AI Hardware

21 Jun 2025
42m
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In this interview, Sam Altman discusses the early days of OpenAI, the decision to pursue AGI, and the challenges they faced, including skepticism from others and competition from DeepMind. He emphasizes the importance of focusing on a unique mission to attract top talent and advises aspiring entrepreneurs to identify m...

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Elon Musk: Digital Superintelligence, Multiplanetary Life, How to Be Useful

21 Jun 2025
49m
AI processed

This interview podcast features Elon Musk at AI Startup School, discussing his journey from Zip2 to his current ventures like SpaceX, Tesla, Neuralink, and XAI. He recounts his early career decisions, including choosing the internet over a PhD at Stanford, and shares key lessons from his experiences, such as the import...

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Andrej Karpathy: Software Is Changing (Again)

19 Jun 2025
39m
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Andrej Karpathy's talk focuses on the evolution of software in the age of AI, introducing the concepts of Software 1.0, 2.0, and 3.0, with an emphasis on large language models (LLMs) as a new programming paradigm. He draws analogies between LLMs and utilities, fabs, and operating systems, highlighting their unique prop...

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Cursor CEO: Going Beyond Code, Superintelligent AI Agents And Why Taste Still Matters

11 Jun 2025
37m
AI processed

In this episode of "How to Build the Future," Garry interviews Michael Truell, CEO of AnySphere, the company behind Cursor, an AI coding platform. Truell discusses Cursor's goal of replacing traditional coding with a more intuitive, AI-driven approach where developers describe what they want and the system builds it. H...

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Fusion Energy Is Tech's Next Big Unlock

06 Jun 2025
8m
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The podcast explores the potential of fusion energy as a clean and virtually limitless power source, addressing the challenges and breakthroughs in fusion research. It features an interview with a representative from Helion Energy, a company employing a novel linear, pulse-driven approach to fusion that uses deuterium...

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AI Apps Are Broken — Here's How To Fix Them

23 May 2025
30m
AI processed

In this episode of The Breakdown, Pete Koomen, a partner at YC and founder of Optimizely, discusses his essay on AI agents and why he believes current approaches to AI development are flawed. He contrasts the empowering experience of using AI coding tools like Cursor and Windsurf with the frustrating experience of AI i...

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How AI Coding Agents Will Change Your Job

09 May 2025
19m
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This episode explores the transformative potential of AI coding agents on software engineering and knowledge work. Against the backdrop of recent advancements in AI, the discussion begins with Tom Blomfield's controversial comparison of software engineers to organic farmers, highlighting the impending automation throug...

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How To Get The Most Out Of Vibe Coding | Startup School

25 Apr 2025
16m
AI processed

This episode explores effective strategies for "vibe coding," a novel approach to software development leveraging AI tools. The speaker, a partner at Y Combinator, shares his experiences and insights gained from experimenting with vibe coding on several side projects. Against this backdrop, he presents advice gleaned...

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How Zepto Became India’s Fastest Growing Startup

18 Apr 2025
38m
AI processed

This episode explores the journey of Aadit Palicha, co-founder and CEO of Zepto, a 10-minute grocery delivery service in India, and the challenges and triumphs of building a successful startup in a competitive market. Against the backdrop of established players like Swiggy, Zomato, and Amazon, Zepto differentiated itse...

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Why America Stopped Innovating - And How We Can Start Again

04 Apr 2025
34m
AI processed

This episode explores the need for a renewed approach to science and technology policy, advocating for a shift from incremental improvements to bold, transformative innovation. Against the backdrop of slow progress on crucial projects like California's high-speed rail, the discussion highlights the detrimental effects...

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