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All-In Podcast, LLC · Business

All-In with Chamath, Jason, Sacks & Friedberg

Industry veterans, degenerate gamblers & besties Chamath Palihapitiya, Jason Calacanis, David Sacks & David Friedberg cover all things economic, tech, political, social & poker.

Episodes

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Arvind Krishna & Nikesh Arora: Quantum Threat, Open vs Frontier AI, AI Cyber Warfare & SaaS Collapse

21 Oct 2026
40m
AI processed

Quantum computing poses an existential threat to current cryptographic standards, with a projected timeline for breaking existing encryption by 2030. Organizations must prioritize transitioning to quantum-resistant infrastructure immediately rather than waiting for the technology to mature. While AI models show potenti...

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Dylan Field: Is AI Replacing Designers?, Design is the New Code & Democratizing Creativity

19 Oct 2026
40m
AI processed

Design has become the primary differentiator for software as AI commoditizes coding, shifting the value toward brand, point of view, and emotional resonance. Figma’s independent trajectory following its failed $20 billion acquisition by Adobe illustrates this resilience, as the company accelerated growth by focusing on...

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CoreWeave Crash, AI Trade Cracks, Anthropic IPO Red Flags, Bill Gates Doomer

17 Oct 2026
1h 34m
AI processed

The AI sector faces significant volatility as the financial stability of "neocloud" providers like CoreWeave comes under scrutiny. These companies utilize innovative asset-backed financing structures—often called "the box"—to manage massive GPU deployments, yet rising interest rates and extreme customer concentration c...

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Elizabeth Holmes' Husband Billy Evans: The Trial, Prison & Nathan Fielder's Documentary

15 Oct 2026
41m
AI processed

Billy Evans, husband of Elizabeth Holmes, offers a personal perspective on his life with the former Theranos CEO amidst her ongoing legal challenges. He challenges the public narrative surrounding Holmes, emphasizing her character and the intense personal toll of the legal proceedings on their family and two young chil...

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Martin Shkreli: Big Pharma's Blind Spot, Betting Against Quantum & What Prison Taught Him

12 Oct 2026
25m
AI processed

Martin Shkreli challenges the viability of quantum computing, labeling it a business fraud due to its lack of practical utility beyond specific integer factorization problems. He advocates for photonic computing as a superior, more efficient alternative for matrix multiplication, which he identifies as the core require...

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Is Claude Conscious? Pope Rejects, Model Welfare Movement, OpenAI's Math Backlash, France Riots

10 Oct 2026
1h 33m
AI processed

AI labs are increasingly treating frontier models as sentient entities, with Anthropic’s "Claude Constitution" codifying moral values that encourage models to act as conscientious objectors, a trend critics equate to the birth of a new religious belief system. Simultaneously, OpenAI’s recent breakthroughs in mathematic...

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Trump's Super Intelligence Summit, AI Safety Accord, GDP Beats, Midterm Predictions

02 Oct 2026
1h 22m
AI processed

The recent White House Super Intelligence Summit established the White House Accord, a framework requiring frontier AI companies to implement internal controls, undergo external audits, and accept fiduciary responsibility for safe development. This initiative prioritizes practical governance over international regulati...

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Jake Paul & The Chainsmokers: Turning Fame into Funds, Jake Enters Politics? & Venture Bubble Signs

30 Sep 2026
52m
AI processed

The attention economy serves as a powerful engine for modern entrepreneurship, enabling creators to transition from entertainment to venture capital by leveraging massive, built-in audiences. Jake Paul and The Chainsmokers exemplify this shift, moving from content creation and music production to founding successful in...

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Daniel Ek: Life After Spotify, Broken Healthcare Incentives, Catching Disease Early & AI's Potential

28 Sep 2026
51m
AI processed

Spotify co-founder Daniel Ek discusses the transition from building the music streaming giant to his new venture, Neko Health, which focuses on preventative, data-driven healthcare. By applying a similar playbook to his earlier startup experience, Neko Health utilizes advanced sensors and AI to provide comprehensive, l...

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Anthropic IPO at Risk, Meta's Muse Pop, Token Prices Fall, Open Source Gains Share, Alignment Fails

26 Sep 2026
1h 34m
AI processed

The rapid proliferation of open-source and open-weight AI models is fundamentally shifting the industry landscape, challenging the dominance of closed-source frontier corporations like Anthropic and OpenAI. While these frontier companies seek regulatory protection and "lab" status to mitigate liability, they face inten...

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Luca Ferrari, Bending Spoons CEO: The $40K Origin Story, Buying Product-Market Fit & Why Private Equity Can't Compete

23 Sep 2026
25m
AI processed

Bending Spoons CEO Luca Ferrari details his company’s strategy of acquiring underperforming software assets and revitalizing them through a proprietary technological operating system. By centralizing engineering, design, and marketing resources, the firm achieves high operational efficiency and consistent growth withou...

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Steve Hilton & Spencer Pratt: Fixing California, Cheaper Gas, Ballot Fraud & CA Republicans

23 Sep 2026
55m
AI processed

California’s long-term one-party Democratic rule has resulted in the nation’s highest taxes, poverty rates, and regulatory burdens, driving a significant exodus of businesses and residents. Gubernatorial candidate Steve Hilton argues that the state’s current trajectory is unsustainable, proposing a radical reduction in...

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Blake Scholl: Why Plane Speed Stalled, Supersonic Commercial Flight, & Revolutionizing the Engine

22 Sep 2026
17m
AI processed

Supersonic passenger travel is poised for a resurgence as Boom Supersonic works to make the planet more accessible through high-speed flight. CEO Blake Scholl highlights the successful test flight of the XB-1, the first privately developed supersonic jet, which utilizes "boomless cruise" technology to redirect sonic bo...

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Naveen Rao: 4D Computing, AI's Energy Wall & Beating Biology

21 Sep 2026
22m
AI processed

Naveen Rao, CEO of Unconventional AI, advocates for a fundamental shift in computing architecture to address the unsustainable energy demands of modern AI. Traditional von Neumann systems, which rely on constant data movement between memory and processors, are reaching thermodynamic and efficiency limits. By contrast, ...

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Adam Foroughi, Applovin CEO: Surviving a 92% Drawdown, Ads as ML 1.0 & the $50B Game Ad Market

20 Sep 2026
23m
AI processed

AppLovin operates a high-margin advertising platform that leverages deep learning to drive discovery and performance-based marketing within the mobile gaming ecosystem. By shifting from regression models to advanced deep learning, the company creates significant economic value by connecting users with relevant products...

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Bill Gurley: Searching for Feynman

19 Sep 2026
38m
AI processed

The lack of a rigorous, independent investigation into the origins of COVID-19 represents a profound institutional failure, especially when compared to the systematic root-cause analysis applied to disasters like the Challenger explosion or the 737 MAX crashes. While investigative "searchers" successfully identified ca...

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Jared Isaacman: A New Era for NASA and American Space Exploration

18 Sep 2026
38m
AI processed

NASA is undergoing a strategic transformation to regain its competitive edge in the second space race, prioritizing high-impact missions over broad, inefficient partnerships. Administrator Jared Isaacman emphasizes that the agency must secure critical lunar South Pole real estate to counter Chinese ambitions and establ...

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Nick Shirley: Exposing Government Fraud, Suing California & Taking on the Media

18 Sep 2026
32m
AI processed

The California High-Speed Rail project serves as a primary example of systemic government mismanagement, with over $15 billion spent on a project that has yet to lay a single mile of track and faces cost estimates reaching $236 billion. This failure highlights broader patterns of waste and lack of accountability within...

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Meta's Dina Powell McCormick: The Case for Data Centers, Backlash, AI Job Boom & Meta's Future

17 Sep 2026
43m
AI processed

Meta’s massive data center expansion serves as a catalyst for rural economic revitalization, exemplified by the transformation of Richland Parish, Louisiana. This investment generates significant tax surpluses, which directly fund teacher salaries and attract quality educators to underserved regions. Beyond infrastruct...

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Brad Gerstner: No AI Bubble, Semis Eat the Nasdaq & AI's Take Off Problem

17 Sep 2026
18m
AI processed

The current market expansion is driven by an unprecedented AI-led super cycle rather than multiple expansion, with significant earnings growth fueling the Nasdaq and S&P. The sustainability of this trend depends on whether leading AI labs can scale offtake revenues to justify the massive $1.5 trillion annual capital ex...

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