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Jason Calacanis · Business

This Week in Startups

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world's greatest founders, operators, investors, and innovators.

Episodes

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Lina Khan’s Figma victory lap, Meta’s Superintelligence Team, BYD mega car-carrier video & MORE | E2160

05 Aug 2025
1h 9m
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In this episode of This Week in Startups, Jason Calacanis and Alex discuss a range of topics, starting with the achievement of consumers getting more for less due to tech companies, contrasting it with government-regulated sectors like housing, healthcare, and education. They delve into Jason's experience at the Nation...

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TWiST 500 interviews with Cortical Labs, Turing, AND Mercor | E2159

01 Aug 2025
1h 23m
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This episode of This Week in Startups, hosted by Lon Harris and Alex Wilhelm, features three interviews from the Twist 500. The initial discussion revolves around Sam Altman's comments on GPT-5 and the broader implications of AI advancements, including potential misuse and the hype surrounding new models. The hosts dis...

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All Star Investor Panel! Sophia Amoruso and Ryan Hoover | E2158

30 Jul 2025
1h 13m
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Figma IPO, IMAX AI Festival, the Tea app spill, that one Sydney Sweeney jeans ad, and more! | E2157

29 Jul 2025
1h 13m
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Behind the scenes at the ALL-IN AI SUMMIT w/ POTUS, JD Vance, Jensen Huang, Lisa Su, and more… | E2156

25 Jul 2025
1h 3m
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AUTOMATING HEALTH CARE, THERMODYNAMIC COMPUTING, AND PRODUCT VELOCITY | E2155

23 Jul 2025
1h 20m
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Manufacturing in the US, Building in Open Source… and more | E2154

21 Jul 2025
1h 22m
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This episode of This Week in Startups features three interviews with founders from Twist 500 companies. The first interview is with John Harris, co-founder and CEO of Harbinger, an EV chassis builder for the medium-duty commercial market, discussing their focus on price parity with diesel vehicles through in-house manu...

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Inside Substack’s $100M Push to Fend Off Beehiiv | E2153

18 Jul 2025
1h 13m
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Thinking Machines’ RECORD seed round, VC Geoff Lewis, and MORE | E2152

17 Jul 2025
1h 8m
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Blitzhiring and the Complicated Case of Windsurf, OpenAI and Google | E2151

14 Jul 2025
1h 0m
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Grok 4 Beats OpenAI + The $300 AI Agent Era | E2150

12 Jul 2025
1h 11m
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Orchestrating Smarter AI Systems with AI21 Labs’ Yoav Shoham | AI Basics with Google Cloud

10 Jul 2025
22m
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Starlink + Tesla? $4T Nvidia? Perplexity Browser? Linda Yaccarino Steps Down? | E2149

09 Jul 2025
1h 6m
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Cloud Seeding, Conspiracies & the Texas Floods | BONUS EPISODE!

09 Jul 2025
26m
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Exits Are Back, QSB Stock & The New America Party? | E2148

07 Jul 2025
1h 7m
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Startup Valuations, Biotech’s Crunch & AI’s Massive TAM | E2147

02 Jul 2025
1h 16m
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In this episode of "This Week in Startups," Alex hosts a panel discussion with investors Astasia Myers (Felicis), Matt Turck (FirstMark), and D.A. Wallach (Time BioVentures) to analyze Q2 dealmaking and investment strategies across different sectors. The conversation covers the dynamics of AI investments, with Myers an...

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The Grammarly–Superhuman Megadeal, plus TWiST 500 chats with LabelBox and Apptronik’s founders | E2146

01 Jul 2025
1h 27m
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Rebuilding Civilization from First Principles: Inside Balaji’s Network State Vision | E2145

30 Jun 2025
1h 4m
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Travis’ Uber Comeback, AGI’s Stakes, Meta’s $100M AI Hires & Prediction Market Gold Rush | E2144

27 Jun 2025
1h 7m
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In this episode of "This Week in Startups," Jason Calacanis and Alex Wilhelm discuss a range of topics, including Travis Kalanick's potential return to Uber through a deal with Pony.ai, DoorDash's drone delivery plans, and the progress of Tesla's self-driving technology. They also explore the rise of prediction markets...

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Multi-Agent AI, Open Protocols & Startup Acceleration with Saurabh Tiwary | AI Basics

26 Jun 2025
19m
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