Sequoia Capital

Biology's Waymo Moment: Ginkgo Bioworks' Jason Kelly

Greetings, Earthlings: Philip Johnston of Starcloud on Data Centers in Space

The First Line of Your Job: Default to AI

The People Who Become Founders “Because It’s Cool” Always Fail

The Most Founder Mode CEO Working Today Isn’t the Founder: Opendoor’s Kaz Nejatian

Physics Gets a Vote: Nominal Cofounders on Hardware Development in an AI World

Ben Horowitz On What Makes a Great Founder

Bayer’s Bill Anderson: Turning a 168 Year-Old Tanker Like a Speedboat

Building the GitHub for RL Environments: Prime Intellect's Will Brown & Johannes Hagemann

Frontier AI research is shifting from simple prompt engineering to deep model customization through post-training and reinforcement learning. By treating "environments"—simulated systems with specific goals and reward functions—as the primary abstraction for model improvement, companies can move beyond off-the-shelf ca...

What’s the Future of Vertical SaaS in an AGI World? Jamie Cuffe, CEO of Pace

LST Vlad Tenev

Making the Case for the Terminal as AI's Workbench: Warp’s Zach Lloyd

Context Engineering Our Way to Long-Horizon AI: LangChain’s Harrison Chase

The discussion centers on long-horizon agents, agent harnesses, and the evolving landscape of AI development. It features Harrison, presumably an expert in the AI field. The conversation highlights the recent advancements in making long-horizon agents functional, particularly in coding and AISREs, where they can produc...

Harvey CEO Winston Weinberg: Why You Should Reinvent Yourself Every 4 Months

How Ricursive Intelligence’s Founders are Using AI to Shape The Future of Chip Design

Palo Alto Networks CEO Nikesh Arora on the Virtues of Being an Outsider

Training General Robots for Any Task: Physical Intelligence’s Karol Hausman and Tobi Springenberg

Physical Intelligence is building robotic foundation models that can enable any robot to perform any task. Karol and Tobi explain that robotics has been bottlenecked by intelligence, not hardware, and that the classical approach of breaking robotics down into perception, planning, and control was fundamentally flawed. ...

Goldman Sachs CEO David Solomon: What Startup Founders Get Wrong About the CEO Job

This special episode features an interview with David Solomon, CEO of Goldman Sachs, where he discusses the firm's culture, decision-making processes, and strategies for long-term success. Solomon shares insights on Goldman Sachs' approach to maintaining its unique culture, adapting to change, and prioritizing client r...

Why the Next AI Revolution Will Happen Off-Screen: Samsara CEO Sanjit Biswas

In this episode, Sanjit Biswas, founder and CEO of Samsara, discusses physical AI, its constraints, and opportunities. He shares his journey from MIT's RoofNet project to founding Meraki and then Samsara, emphasizing the importance of building impactful technologies. Sanjit highlights the significance of connectivity, ...

Hard Mode: Hypergrowth from Europe with Mati (ElevenLabs) and Anton (Lovable)