
Sequoia Capital
We help the daring build legendary companies – from idea to IPO and beyond.
Episodes


Andrej Karpathy: From Vibe Coding to Agentic Engineering
The transition to "Software 3.0" marks a fundamental shift where programming evolves into prompting and leveraging LLMs as autonomous agents. This paradigm, characterized by "vibe coding" and agentic engineering, enables rapid development but necessitates a rigorous focus on verifiability and quality control. While AI ...

Demis Hassabis on Building DeepMind, AlphaFold, and the Final Stretch to AGI
Demis Hassabis, co-founder of DeepMind, traces his career trajectory from chess prodigy and game developer to pioneer in artificial general intelligence (AGI). His early work in gaming and neuroscience provided the foundational insights for building DeepMind, where the core mission remains solving intelligence to addre...

"If you are just going on vibes, you will fail" | Profound CEO James Cadwallader #ai #podcast

A "dead internet" could happen within 3 years | Profound CEO James Cadwallader #ai #podcast

The Rule MIT Uses to Stay at the Top for 150 Years

MIT’s president on one of AI’s biggest blind spots
MIT President Sally Kornbluth explores the integration of artificial intelligence into higher education, emphasizing that AI should augment rather than replace human performance. Students must maintain foundational skills like basic coding and writing because these disciplines are essential for verifying AI accuracy an...

Jack Dorsey: "I hired a CEO coach and learned nothing" — Here's what he did instead #podcast

MIT's president was summoned to Congress 11 Months Into the Job. She survived.

ChatGPT, Claude & Gemini recommend brands differently | Profound CEO James Cadwallader #ai #podcast

Does Education Matter in the Age of AI? MIT President Sally Kornbluth

ChatGPT used 65 web pages to find a showerhead. Profound CEO James Cadwallader

AI didn't change the front door. The visitor changed. Profound CEO James Cadwallader #ai #podcast

From SEO to Agent-Led Growth: Profound's James Cadwallader

Roelof Botha: From Command-and-Control to Ground-Truth Signals #ai #founders

Jack Dorsey: How to Build a Board That Actually Helps Your Company #podcast #ceo

Jack Dorsey: How Conversational Interfaces Reveal What Customers Really Want #ai #podcast

Jack Dorsey: Every Company Can Now Be a Mini-AGI
Traditional corporate hierarchies are increasingly obsolete, necessitating a shift toward intelligence-based organizational structures where AI serves as the core operating system. By treating a company as a living model, organizations can replace rigid management layers with data-driven workflows, enabling faster deci...

Oura’s Tom Hale: What People Don’t Tell You About Being CEO

AI Meets Biochemistry: Redefining the Lab with Robotic Experiments
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