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Dave Asprey · Health

The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio , he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization. Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more. This isn’t just self-improvement - it’s human enhancement backed by data. Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life. Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

Episodes

Eat THESE Anti-Aging Mushrooms to Live Longer (Paul Stamets) : 1327

MIT Neuroscientist: The Ultimate Nootropic For Memory : 1326

How To Deal With The Fear Of Death (Ethics Of Longevity) : 1325

The Hidden Traps of “Healthy” Eating (Biohacking Daily Nutrition) : 1324

Sulforaphane, Curcumin, and NEW GLP-1 Drugs (Biohacking for Longevity) : 1323

Dave Asprey interviews David Roberts and Dr. John Gildaya about the benefits and drawbacks of broccoli, the three phases of liver detox, and the importance of sulforaphane for activating all three detox pathways. They discuss how sulforaphane, found in broccoli seeds, can protect against glyphosate-induced leaky gut an...

Mast Cells Explained: Biohacking Inflammation, Allergies, and Brain Fog : 1322

What Is Uric Acid and How Does It Predict Your Longevity : 1321

Hacking Dopamine Naturally: Pain, Focus, and Performance : 1320

You Have A 25% Chance to Lose All Your Memory (Longevity Secrets) : 1319

The Hormone War Dividing Female and Male Longevity : 1318

The 10-Second At-Home Walk Test for Longevity (Easy Biohack) : 1317

PhD at MIT: The Longevity Molecule That Reverses Aging (250 Studies) : 1316

Still Fasting in 2025? Here’s How to Make It Work Better : 1315

How to Make Life-Changing Decisions Without Fear – Joe Hudson : 1314

The New Poisons Lurking Around You – Save Your Longevity : 1313

Jim Kwik: What I Take to Biohack Brain Speed and Focus : 1312

Why I Inject a “Female Hormone” 3x a Week (Nootropic Hacking) : 1311

Top 5 Dopamine Boosting Biohacks for Superhuman Energy : 1310

Protein vs. Plants: The 50g-a-Meal Biohacking Rule : 1309

The Air Force Uses This Mind-Bending Sound Biohack — Try It Yourself! : 1308

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