The Proof with Simon Hill

Has Optimisation Culture Gone Too Far? | Sarah Ann Macklin

What the Headlines Get Wrong About the Future of Meat | Bruce Friedrich

Improving cholesterol and blood pressure with diet | A Masterclass

Cardiovascular health relies on managing cholesterol and blood pressure through targeted dietary and lifestyle interventions. Legumes serve as a foundational food group, offering fiber and plant protein that consistently correlate with reduced mortality. Managing ApoB levels involves limiting saturated fat in favor of ...

The Peptides Quietly Accelerating Aging | Dr Valter Longo

Peptides, including growth hormone secretagogues and GLP-1 receptor agonists, are increasingly used for weight loss and anti-aging despite significant, under-researched long-term health risks. Dr. Valter Longo, a longevity researcher with three decades of experience, explains that chronically elevating growth hormone a...

The Diet That Lowers Cholesterol Like a Statin | Dr Andrea Glenn

Nutrition epidemiology provides essential insights into long-term health outcomes when triangulated with clinical trials and mechanistic data. Research indicates that higher plant-to-animal protein ratios, particularly when combined with protein-dense sources like legumes and nuts, significantly reduce cardiovascular d...

Food Labels, Fibre, and Ultra-Processed Foods: What Really Matters | Rhiannon Lambert

Ultra-processed foods now constitute over half of the average diet in Western nations, creating significant confusion and anxiety for consumers. Rather than adopting a fear-based approach that demonizes all processed items, nutritionists emphasize the "food matrix" and the critical role of fiber in maintaining gut and ...

The Peptide Lie: What a Drug Developer Reveals About the Compounds Everyone Is Injecting | Dr Leigh Baxt

The surge in the use of non-FDA-approved peptide therapies for wellness and longevity presents significant, unquantifiable health risks due to a lack of rigorous human clinical data. While peptides can be legitimate therapeutic tools, many compounds currently marketed for "research purposes only" bypass the essential 1...

Preventing and reversing osteoporosis | Dr Belinda Beck

Bone health requires a shift from cautious, low-impact recommendations toward high-intensity resistance and impact training to effectively build bone mineral density. Dr. Belinda Beck, director of the Bone Densitometry Research Laboratory, demonstrates that contrary to conventional medical wisdom, heavy loading is safe...

New microbiome science | Dr Tim Spector

The gut microbiome functions as a critical indicator of metabolic health, shifting the focus from simple diversity metrics to a more precise ratio of beneficial to pathogenic bacteria. Dr. Tim Spector, a professor of genetic epidemiology, introduces a validated ranking system derived from metagenomic sequencing of 35,0...

Food and weight loss | Dr Kevin Hall

The podcast explores the complexities of ultra-processed foods and their impact on health, featuring Dr. Kevin Hall, a nutrition scientist known for his metabolic ward studies. Hall discusses the new dietary guidelines for Americans, highlighting the surprising inclusion of highly processed foods despite limited prior ...

The exercise that builds strong bones and better balance | Dr Lora Giangregorio

This podcast addresses the critical importance of bone health, often overlooked until a fracture occurs, despite its significant impact on mobility, independence, and mortality. Dr. Lora Giangregorio, Research Chair in Bone Health and Exercise Science, explains that fractures, especially hip and spine fractures, lead t...

The dietary guidelines great debate | Dr Christoper Gardner and Dr Ty Beal

The sleep habit that quietly raises your risk of heart disease | Dr Kristen Knutson

The podcast explores the science of sleep and circadian rhythms, emphasizing that optimal health depends not only on sleep duration but also on timing, regularity, and synchronicity with internal biological clocks. Dr. Kristen Knutson, a sleep and circadian researcher, explains how light exposure, meal timing, and exer...

The Science of Exercise for Women 40+: What to Prioritise (And What to Ignore) | Dr Lauren Colenso-Semple and Dr Alyssa Olenick

Exercise for women in their 40s, 50s, and 60s is explored, addressing the confusion and loss of confidence many women experience despite their efforts. The discussion highlights the importance of resistance training for maintaining muscle mass, physical function, and long-term health, while cautioning against using exe...

Building muscle for longevity | Dr Brad Schoenfeld and Alan Aragon

The podcast explores the critical role of muscle physiology in healthy aging, challenging the notion of inevitable age-related muscle loss. It features insights from muscle science researcher Brad Schoenfeld and nutrition expert Alan Aragon, who discuss how resistance training and proper nutrition can significantly cou...

The good and the bad of the new US dietary guidelines | Dr David Katz

Reversing atherosclerosis with diet | Simon Hill, Msc

The podcast addresses the possibility of reversing atherosclerosis through diet and lifestyle changes. It highlights six randomized controlled trials examining the impact of nutrition on atherosclerosis. The host emphasizes that atherosclerosis isn't an inevitable part of aging but a disease influenced by lifestyle cho...

How body fat affects your metabolic health and risk of metabolic disease | Dr Robert Eckel

The science of fertility: Hormones, inflammation, and what you can control | Dr Natalie Crawford

Fertility is a complex, proactive health journey rather than a matter of chance, heavily influenced by metabolic health, chronic inflammation, and daily lifestyle choices. Dr. Natalie Crawford, a reproductive endocrinologist, emphasizes the concept of "Trimester Zero," where individuals optimize egg and sperm quality m...

Why some people gain weight eating the same food | Dr Karen Corbin

Gut microbiome composition significantly influences how much usable energy the body extracts from food, challenging the traditional view that weight gain is solely a function of caloric intake. Registered dietitian and scientist Dr. Karen Corbin explains that individuals can absorb over 100 calories more or less daily ...