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All-In Podcast, LLC · Business

All-In with Chamath, Jason, Sacks & Friedberg

Industry veterans, degenerate gamblers & besties Chamath Palihapitiya, Jason Calacanis, David Sacks & David Friedberg cover all things economic, tech, political, social & poker.

Episodes

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Anthropic S-1 Shocker, Greatest Business Ever? Google's $500B Wipeout, Midterm Predictions

30 Oct 2026
1h 25m
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Anthropic’s S-1 filing reveals a highly capital-efficient business poised for a record-breaking IPO, with revenue growth driven by massive enterprise demand and compute multipliers. The company’s trajectory highlights a broader shift where a handful of AI-focused firms now command capital flows comparable to government...

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WHOOP CEO, Will Ahmed: 50B Hours of Health Data, a 4 Million Member Data Moat, & the FDA Fight

29 Oct 2026
55m
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Arvind Krishna & Nikesh Arora: Quantum Threat, Open vs Frontier AI, AI Cyber Warfare & SaaS Collapse

21 Oct 2026
40m
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Quantum computing advancements threaten existing cryptographic standards, necessitating an immediate transition to quantum-resistant infrastructure before the projected 2030 breakthrough. While AI models currently offer significant efficiency gains, their integration into enterprise stacks requires balancing cost-effec...

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Dylan Field: Is AI Replacing Designers?, Design is the New Code & Democratizing Creativity

19 Oct 2026
40m
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Design has emerged as the primary differentiator in software development as AI-driven coding models commoditize technical implementation. Dylan Field, CEO of Figma, argues that while AI lowers the barrier to entry for production, it fails to raise the creative ceiling, which remains the domain of human intent and bold,...

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CoreWeave Crash, AI Trade Cracks, Anthropic IPO Red Flags, Bill Gates Doomer

17 Oct 2026
1h 34m
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Elizabeth Holmes' Husband Billy Evans: The Trial, Prison & Nathan Fielder's Documentary

15 Oct 2026
41m
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Martin Shkreli: Big Pharma's Blind Spot, Betting Against Quantum & What Prison Taught Him

12 Oct 2026
25m
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Quantum computing is a technological "fugazi" with limited practical utility, as current machines lack the speed and storage capabilities to outperform classical systems like NVIDIA’s GPUs. While AI represents a significant shift in productivity, the current hype cycle is fueled by massive capital inflows rather than i...

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Is Claude Conscious? Pope Rejects, Model Welfare Movement, OpenAI's Math Backlash, France Riots

10 Oct 2026
1h 33m
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Trump's Super Intelligence Summit, AI Safety Accord, GDP Beats, Midterm Predictions

02 Oct 2026
1h 22m
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The White House Super Intelligence Summit convened industry leaders to establish the White House Accord, a framework requiring frontier model companies to implement internal controls and undergo external audits. This agreement shifts safety oversight to corporate boards, creating a fiduciary duty to manage risks withou...

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Jake Paul & The Chainsmokers: Turning Fame into Funds, Jake Enters Politics? & Venture Bubble Signs

30 Sep 2026
52m
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Daniel Ek: Life After Spotify, Broken Healthcare Incentives, Catching Disease Early & AI's Potential

28 Sep 2026
51m
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Anthropic IPO at Risk, Meta's Muse Pop, Token Prices Fall, Open Source Gains Share, Alignment Fails

26 Sep 2026
1h 34m
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The rapid proliferation of open-source and open-weight AI models is fundamentally shifting the industry from a closed-source frontier to a commoditized, ubiquitous landscape. While major AI corporations frame themselves as research labs to mitigate liability, their for-profit nature necessitates accountability for prod...

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Luca Ferrari, Bending Spoons CEO: The $40K Origin Story, Buying Product-Market Fit & Why Private Equity Can't Compete

23 Sep 2026
25m
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Steve Hilton & Spencer Pratt: Fixing California, Cheaper Gas, Ballot Fraud & CA Republicans

23 Sep 2026
55m
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Blake Scholl: Why Plane Speed Stalled, Supersonic Commercial Flight, & Revolutionizing the Engine

22 Sep 2026
17m
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Naveen Rao: 4D Computing, AI's Energy Wall & Beating Biology

21 Sep 2026
22m
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Adam Foroughi, Applovin CEO: Surviving a 92% Drawdown, Ads as ML 1.0 & the $50B Game Ad Market

20 Sep 2026
23m
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Bill Gurley: Searching for Feynman

19 Sep 2026
38m
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Rigorous, independent investigation into the origins of COVID-19 is essential to prevent future global health catastrophes. Drawing on the "CAPA" (Corrective and Preventive Action) framework, the failure to identify a definitive root cause for the pandemic stands in stark contrast to successful investigations of traged...

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Jared Isaacman: A New Era for NASA and American Space Exploration

18 Sep 2026
38m
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Nick Shirley: Exposing Government Fraud, Suing California & Taking on the Media

18 Sep 2026
32m
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