No Priors: Artificial Intelligence | Technology | Startups

Democratizing Security for the Agentic Web with CloudFlare CTO Dane Knecht

Revolutionizing Cybersecurity and AI-Driven Science with OpenAI President Greg Brockman

AI is fundamentally transforming scientific discovery, moving beyond simple arithmetic to resolving long-standing mathematical problems and offering potential breakthroughs in biology and drug discovery. This shift necessitates a reevaluation of cybersecurity, where AI-driven defense mechanisms must address systemic "t...

Beam: The Great American Open Model with ReflectionAI Co-Founder and CEO Misha Laskin

Building frontier open-weight models requires a tightly coupled approach combining pre-training and reinforcement learning to achieve competitive intelligence density. Misha Laskin, CEO of ReflectionAI, argues that open models are essential for enterprise autonomy, allowing organizations to transition from renting clos...

The Future of Frontier Model Architectures with Walter Goodwin, Fractile Founder and CEO

AI inference requires a fundamental shift in chip architecture, moving beyond traditional flop-centric designs to prioritize extreme memory bandwidth. Fractile, led by CEO Walter Goodwin, addresses this by developing chips that enable multi-trillion parameter models to run at thousands of tokens per second. By moving a...

Re-Founding Incumbents for the AI Era with Sequence Holdings Co-Founder and CEO Michael Lee

Why Diffusion Will Win AI Inference with Inception Co-Founder and CEO Stefano Ermon

Coinbase’s Everything Exchange: Agentic Finance, Stablecoins, and Tokenization with CEO Brian Armstrong

Redefining Chip Architecture with Arm CEO Rene Haas

Arm CEO Rene Haas details the company's strategic evolution from a pure IP licensing model to providing compute subsystems and physical chip products, driven by the industry's need for faster time-to-market. While AI accelerators dominate current headlines, CPUs remain the essential heart of all computing, responsible ...

Rethinking Legacy Data Infrastructure with Eon Co-Founders Ofir Ehrlich and Gonen Stein

From Restoring Sight to Reimagining the Brain, with Max Hodak

How Nuclear Will Unlock Energy Abundance with Valar Atomics Founder Isaiah Taylor

Building a $200M Bootstrapped Chess Empire with Chess.com CEO Erik Allebest

Chasing Trillion-Dollar Companies, Founder Ambition, Token Budgets, and Regulatory Capture with Sarah & Elad

Building an Autonomous Enterprise for Real-World Services with Netic Founder Melisa Tokmak

Building an Autonomous Delivery Experience with DoorDash Co-Founders Andy Fang and Stanley Tang

Travel Through the Lens of AI with with Booking.com CEO Glenn Fogel

Why Traditional Benchmarks Fail Modern AI Models with OpenAI Research Scientist Noam Brown

Re-engineering the Semiconductor Supply Chain with Intel CEO Lip Bu Tan

Biohub: The Future of Biology is Open-Source with Co-Founders Mark Zuckerberg, Priscilla Chan, and Head of Science Alex Rives

We Need An Ecosystem in AI, And Every Company Can Win A Place In It

Microsoft’s AI strategy centers on fostering an ecosystem where enterprises leverage multi-modal "harnesses" to build proprietary, frontier-level intelligence. By integrating private evaluations, specific business data, and specialized tools, companies can move beyond generalist models to create durable, compounding va...