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Y Combinator · Business

Y Combinator

Episodes

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Alexandr Wang: From Los Alamos to Superintelligence

29 Jul 2026AI processed

Alexandr Wang, founder of Scale AI, details his journey from a math-focused youth in Los Alamos to building a foundational company in the AI ecosystem. He emphasizes the critical role of data in training models, noting that early skepticism from investors shifted as the industry recognized data as a primary business op...

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Blake Scholl: "The Future Was Supposed to Be Faster"

28 Jul 2026
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Sam Altman: "Never a Better Time to Do a Startup"

28 Jul 2026AI processed

The current technological landscape offers unprecedented opportunities for founders to launch ambitious, high-impact startups by leveraging AI to drastically reduce development cycle times and costs. While the rapid advancement of AGI raises valid concerns regarding safety and power concentration, the most effective pa...

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Boris Cherny: Building Claude Code

27 Jul 2026AI processed

Building agentic products requires an empirical, scientific mindset that prioritizes "unhobbling" models by removing rigid, outdated system prompts and scaffolding. As models like Opus 5 evolve, they frequently outperform the constraints imposed by legacy engineering practices. Developers should embrace an ablation-bas...

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Jensen Huang: The Mindset That Built NVIDIA

26 Jul 2026AI processed

NVIDIA’s ascent to a trillion-dollar leader in accelerated computing stems from a relentless commitment to first-principles thinking and the ability to pivot when core technologies fail. Early struggles, such as the flawed 3D graphics algorithm that necessitated a desperate, textbook-driven reinvention, underscore the ...

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Self-Maintaining APIs

26 Jul 2026
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What Actually Makes A Startup Durable

25 Jul 2026
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AI-Native Compliance Infrastructure

25 Jul 2026
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Proving You’re Human

25 Jul 2026
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What Big Tech Missed And How Startups Can Still Win

25 Jul 2026
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Why Physical AI Is the Next Platform Shift

25 Jul 2026
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Data for the Real World

25 Jul 2026
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New Operating Systems for the Physical World

24 Jul 2026
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How Two French Engineers In New York Built The Company That Monitors The Entire Cloud

24 Jul 2026
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Opencode CEO: Blocked, 20X Growth in 6 Months, Building the Coding Agent for the World

24 Jul 2026
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How Photoroom Trained Themselves To Dream Bigger

24 Jul 2026
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The Best Time to Build in Crypto

24 Jul 2026
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AI for the Aging Population

23 Jul 2026
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Scientists Are Built for Startups

23 Jul 2026
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The Model-Agnostic AI Platform Betting That No Single Lab Will Win

23 Jul 2026
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