

Vital Signs with Jacob Effron and Nikhil Krishnan
On Vital Signs, Jacob Effron and Nikhil Krishnan dig into cutting-edge trends in healthtech and the people shaping them. Every two weeks they’ll explore a new sub-sector and trend with policy leaders, startup founders and industry executives. Subscribe now to make sure you don’t miss any of it!
Episodes


Ep 69: Cadence Founder Chris Altchek on the Future of Chronic Disease Care

Ep 68: Garner Health Founder on Measuring Doctor Quality, The AI Landscape & What Improves Healthcare

Ep 67: Abridge Leaders on AI-Native Healthcare, Doctors Who Code, and the Future of Clinical AI

Ep 66: Pete Shalek On The Future of Front Office Automation

Ep 65: CMMI Leaders on ACCESS Model Launch, Drug Pricing Strategy, and the Future of Technology Enabled Care

Ep 64: Sutter Health CEO & President Warner Thomas on Digital Transformation and the Future of Health Systems

Ep 63: Narayana Health Vice Chairman on Scaling Quality Care in India and Tech’s Role

Ep 62: Merck KGaA Chief Data and AI Officer on Scaling AI in Pharma and The Future of Enterprise Software

Ep 61: Co-Founder of Chai Discovery Joshua Meier on 99% Faster Drug Discovery, BioTech’s AlphaGo Moment, Building Photoshop for Molecules
The podcast explores the current state and future potential of AI in drug discovery, featuring Joshua Meier, CEO and co-founder of Chai Discovery. Meier discusses the evolution of AI in biology, from early deep learning models for protein folding to the latest foundation models capable of de novo design. He highlights ...

Ep 60: General Medicine's Elliot Cohen on Lessons from PillPack and Amazon and The Future of AI x Healthcare

Flashback: Hinge Health CEO Daniel Perez on Effective Employer Sales, Patient Engagement and His Top Advice to Founders

Ep 59: Photon Health CEO Otto Sipe on the Future of Pharmacies, PBMs and GLP-1s
This episode explores the evolution and current state of e-prescribing and the broader pharmacy industry, featuring Otto Sipe, CEO of Photon Health. Against the backdrop of a near-monopoly in e-prescribing held by SureScripts, the discussion highlights Photon's innovative approach to reorienting the prescription around...

Ep 58: Iora Health Former CEO Rushika Fernandopulle on Current State of Value Based Care Across Payer Types and AI’s Role in Primary Care

Ep 57: Taro Health CEO Frank Wu on Direct Primary Care, The History of InsurTech and AI for Payers
This podcast interviews Frank Wu, CEO of Taro Health, a new health insurance carrier, about the challenges and strategies of building a health insurance company from the ground up. The discussion covers the mistakes of previous InsurTech startups (over-reliance on pricing), Taro's unique approach of partnering with Di...

Ep 56: Providence CEO Erik Wexler on Evaluating Partnerships, Policy and Leadership
This podcast features an interview with Erik Wexler, CEO of Providence Health, a large US health system. The conversation covers key priorities for health systems in 2025, focusing on AI adoption (specifically in behavioral health assessments), operational efficiency, and strategic partnerships. Wexler emphasizes the...

Ep 55: Hinge Health CEO Daniel Perez on Effective Employer Sales, Patient Engagement and His Top Advice to Founders

Ep 54: General Catalyst CEO Hemant Taneja on Buying a Health System, $100B Healthcare Companies and The Future of AI and Venture
Healthcare transformation relies on "health assurance," a model prioritizing proactive, affordable, and accessible care through radical collaboration with existing health systems rather than external disruption. Achieving this requires building category-defining platforms that bridge the gap between technology and clin...

Ep 53: Cradle CEO Stef van Grieken on the State of AI x Bio and Selling SaaS to Pharma
In this episode of the Vital Signs podcast, host Stef van Grieken, co-founder and CEO of Cradle Bio, shares insights into the evolving role of AI in biotechnology. He notes that the field is still in its infancy, comparable to the early stages of GPT technology. Cradle Bio leverages AI to significantly speed up protein...

Ep 52: knownwell CMO Dr. Angela Fitch on The Future of GLP-1s and New Approaches to Obesity Medicine
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