Your guide to the AI revolution, co-hosts Elad Gil and Sarah Guo talk to the world's leading engineers, researchers and founders about the biggest questions: How far away is AGI? What markets are at risk for disruption? How will commerce, culture, and society change? What’s happening in state-of-the-art in research? Email feedback to [email protected]. Sarah Guo is a startup investor and the founder of Conviction, an investment firm purpose-built to serve intelligent software, or "Software 3.0" companies. She spent nearly a decade incubating and investing at venture firm Greylock Partners. Elad Gil is a serial entrepreneur and a startup investor. He was co-founder of Color Health, Mixer Labs (which was acquired by Twitter). He has invested in over 40 companies now worth $1B or more each, and is also author of the High Growth Handbook.
In this episode of No Priors, Sarah and Elad interview Brandon McKinzie and Eric Mitchell from OpenAI about their O3 reasoning model. The discussion covers the advancements in O3, including its enhanced ability to think before responding and utilize tools like web browsing and code execution to solve complex tasks. The...
This episode explores the development and capabilities of OpenAI's Deep Research, a new agentic product released in February. Against the backdrop of advancements in reinforcement learning algorithms, the creators sought to apply these to everyday user tasks, focusing initially on online browsing and research tasks ra...
This episode explores the challenges and innovations in mineral exploration, specifically focusing on KoBold Metals' AI-driven approach. Against the backdrop of dwindling success rates in traditional mineral exploration, KoBold leverages a vast dataset encompassing historical records, satellite imagery, and geophysica...
This episode explores the evolving landscape of AI model training data acquisition and talent assessment, featuring Brendan Foody, CEO of Mercor. Against the backdrop of Mercor's rapid growth in recruiting individuals to train AI models, the discussion delves into the skills currently sought by leading AI labs—ranging...
This episode explores the rapid advancements in AI image generation and their implications for various industries. Against the backdrop of recent market fluctuations, the hosts discuss the ongoing evolution of image generation technology, highlighting milestones like the GAN wave and the emergence of models like Midjo...
In this episode of No Priors, Shiv Rao, CEO and founder of Abridge, discusses how his company uses AI to alleviate the clerical burden on clinicians, allowing them to focus more on patient care. Rao explains Abridge's evolution, its focus on conversations as the primary signal in healthcare, and its strategic decision ...
This episode explores the challenges and opportunities in building general-purpose AI for robotics, featuring Chelsea Finn, co-founder of Physical Intelligence. Against the backdrop of robotics' historical focus on narrow applications, Finn discusses her company's ambitious goal of creating a single neural network mod...
This podcast interviews Noubar Afeyan, founder and CEO of Flagship Pioneering, a firm behind Moderna and other biotech companies. The discussion covers Afeyan's entrepreneurial journey, his company's approach to fostering emergent innovation (emphasizing variation, selection, and iteration over rigid goal-setting), an...
The release of Tahoe-100, the world’s largest single-cell drug-perturbed dataset, marks a pivotal shift toward building virtual cell models that simulate biological responses to drugs and genetic edits. By providing 100 million single-cell data points across 50 cancer models and 1,200 drug treatments, this resource ena...
In this episode of No Priors, Sarah interviews Winston Weinberg, co-founder and CEO of Harvey, an AI platform for legal and professional services. Weinberg discusses the company's origins, inspired by GPT-3's potential to transform legal workflows, and its mission to build an AI platform applicable across various profe...
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