

Minus One
A show about the winding journeys the world's most interesting people take to becoming great—and what they do when figuring out a question we all face: What's Next? Because before you launch at Zero, you have to figure out what to launch at Minus One. Hosted by South Park Commons Partner Aditya Agarwal and members of the SPC community.
Episodes


How Waymo Made Self-Driving Cars a Reality | Dmitri Dolgov, Co-CEO

The Blood Test That Could Detect Thousands of Diseases | Helmy Eltoukhy, Guardant Health

OpenAI's ex-B2B CTO on Keeping AI Aligned
Navigating the rapid evolution of artificial intelligence requires a shift from passive observation to active participation, where individuals must break preset mindsets to master emerging technologies. Srinivas Narayanan, a veteran of Meta and OpenAI, emphasizes that building impactful AI solutions demands high agency...

The Secret Superpower of Great Founders | Sridhar Ramaswamy (Snowflake CEO)

What Is Reward Hacking and Can We Stop It? | Tom McGrath, Goodfire

Anthropic Engineer on the Future of Coding with AI | Thariq Shihipar
AI development currently faces a "capability overhang," where models possess intelligence exceeding the current ability of users and harnesses to fully utilize them. Building effective agentic systems requires moving beyond simple prompting to creating custom harnesses that allow models to build their own context and e...

The Man Who Took India to the International Space Station | Shubhanshu Shukla

Minus One to Space Gun | Nato Saichek

Why Great AI Companies Are Moving Beyond Tools | Amit Jain (Luma AI)

The AI Cybersecurity Crisis Is Here | Nikesh Arora (Palo Alto Networks CEO)
AI is fundamentally transforming cybersecurity by accelerating both the discovery of vulnerabilities and the speed of potential exploits, requiring enterprises to adopt new control frameworks for agentic systems. Organizations must move beyond traditional security models to address the risks posed by non-deterministic ...

How Replit Is Enabling a New Wave of Million-Dollar Founders | Amjad Masad & Haya Odeh
Programming is shifting toward a post-prompting era where autonomous agents and intuitive interfaces replace traditional manual coding. Replit founders Amjad and Haya Odeh emphasize that the future of software development lies in making programming accessible to domain experts, not just professional engineers. By integ...

Anthropic CTO on AI Safety in the Age of Exponential Growth | Rahul Patil
Rahul Patil, CTO of Anthropic, discusses his journey into computer science, driven by a childhood desire to hack video games and a fascination with exponential growth. Patil emphasizes curiosity and continuous self-improvement, advocating for a focus on personal growth rather than competition. He recounts his move to t...

Elad Gil: Silicon Valley’s Most Dangerous Startup Advice
Navigating the "minus one" stage of startup development requires extreme speed and a relentless focus on customer-centricity, as current market conditions offer unprecedented openness to AI adoption. Successful founders identify viable markets early, avoiding the common pitfall of clinging to failing ideas for too long...

What Gamma ($2B Unicorn) Learned that Most Founders Get Backwards | Grant Lee
Gamma founder Grant Lee navigates the challenges of disrupting the presentation software market, currently dominated by incumbents like PowerPoint and Google Slides. Success hinges on driving fundamental behavior change rather than merely offering incremental feature improvements, requiring a focus on mobile-friendly, ...

We Asked DoorDash’s CEO If AI Competitors Scare Him

Andrew Yang: AI's "Job-Killing Tsunami" + Why He'll Pay You Not to Use Your Phone
Andrew Yang, former presidential candidate and entrepreneur, discusses themes of agency, societal problems, and potential solutions. Yang reflects on his early career, influences, and the development of his pessimistic outlook on job displacement due to AI, contrasting it with his optimistic drive to build solutions. H...

You Don't Need "Passion" to Build a $1B+ Company | Pilot CEO Waseem Daher

Betting an Entire Company on AI, Bubble or Not | Render CEO Anurag Goel

How Asking ‘Why?’ Changes What You Build | Kunal Shah
Entrepreneurial success hinges on understanding core human motivations rather than merely building technical solutions. Founders often fail by attempting to create new consumer needs instead of identifying existing "rivers" of motivation and building efficient "dams" to capture them. Curiosity, particularly the "why" q...
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