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Nick talks with Prof. Lutz Schomburg about selenium biology in the endocrine system: selenoprotein P as the liver’s selenium transport protein and status biomarker, autoantibodies that can impair delivery despite normal blood selenium, thyroid autoimmunity (Hashimoto’s and Graves’), diabetes, aging, and what selenium supplementation trials show.

TOPICS DISCUSSED:

• Selenoprotein P: Liver-made transport protein that delivers selenium to tissues and serves as a status biomarker beyond total serum selenium.

• Autoantibodies & Delivery: Anti-SELENOP antibodies can impair selenium delivery even when blood selenium looks normal.

• Thyroid Autoimmunity: Links between selenium status and Hashimoto’s / Graves’ disease risk and course.

• Supplementation Trials: What controlled selenium trials do and do not show for thyroid and metabolic outcomes.

• Diabetes & Aging: How selenium biology intersects with diabetes risk and aging.

• Practical Context: Interpreting selenium blood tests and why a “normal” result can still miss tissue delivery problems.

*Not medical advice.

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Selenium, Thyroid Autoimmunity & Selenoprotein P | Lutz Schomburg | Episode 308

Mind & Matter

Selenium, Thyroid Autoimmunity & Selenoprotein P | Lutz Schomburg | Episode 308