25 Jan 2026
22m

The Natural Ozempic In Your Gut (Eat THIS To Switch It On) : 1404

Podcast cover

The Human Upgrade: Biohacking for Longevity & Performance

Dave Asprey discusses how to activate the body's natural GLP-1 system as an alternative to drugs like Ozempic for weight loss. He argues that hunger is a hormonal issue, not a math problem of calories in versus calories out, and that Ozempic overrides rather than repairs the natural appetite system. Asprey suggests strategies to stimulate natural GLP-1 production, including shifting from constant snacking to structured meals with protein and fiber, identifying and reducing intake of liquid sugar and processed foods, and incorporating resistant starch sources like green banana flour to boost butyrate production in the gut. He emphasizes the importance of a healthy gut microbiome, achieved by consuming fiber-rich foods, reducing stress, and creating a 12-14 hour overnight fasting window to allow the gut to repair itself.

Outlines

Part 1: Hormones, Hunger, and the Gut

Part 2: Natural GLP-1 and Resistant Starch

Part 3: Gut Repair and Modern Threats

Part 4: Lifestyle Optimization and Conclusion

Sign in to continue reading, translating and more.

Open full episode in Podwise