NEJM This Week — July 31, 2025

This New England Journal of Medicine podcast episode from July 31st, 2025, covers a range of medical topics, including measurable residual disease guided therapy in myeloma, mitochondrial DNA disease and related reproductive care pathways, acute normovolemic hemodilution in cardiac surgery, and resolution of squamous cell carcinoma by restoring T-cell receptor signaling. It also addresses motor vehicle crash prevention strategies, a case report of a woman with seizure-like activity and odd behaviors, and the evaluation of occupational pulmonary impairment, as well as perspectives on Covid-19 vaccines, public policies, and the experience of living with chronic disease. Additionally, the episode features images in clinical medicine related to spontaneous intracranial hypotension and neovascularization in retinopathy of prematurity.