E60: The 2021 Bestie Awards PLUS Jack Dorsey starts the Web3 Wars

In this year-end episode of the All-In Podcast, Jason Calacanis, David Friedberg, David Sacks, and Chamath Palihapitiya present their "Bestie Awards" for 2021, covering the biggest winners and losers in politics and business, the biggest surprises, best science breakthroughs, and worst trends. They debate topics such as the performance of President Biden, the rise of the retail investor, the impact of woke politics, and the potential of new technologies like DAOs and plasma fusion. They also discuss personal favorites, including books, movies, and music, and reflect on the dynamics of their own relationships as co-hosts.

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All-In Podcast

Introduction to the 2021 Bestie Awards

Biggest Winner in Politics

Joe Manchin's Impact and Biggest Loser in Politics

The Progressive Left, Alt-Right, Kamala Harris, and Tony Fauci as Political Losers

Biggest Political Surprise: Youngkin's Victory and Harris's Sideline

Speculation on Kamala Harris's Future and Analysis of the Build Back Better Failure

Biggest Winner and Loser in Business

Chinese Billionaires, Big Tech, and Meta as Business Losers

Biggest Business Surprise: Miami's Tech Boom and the Rise of DAOs

Moderna/BioNTech and Oral COVID Antiviral Pills as Breakout Companies and Science Breakthroughs

Concerns About Antiviral Side Effects and CRISPR Gene Editing

SpaceX Starship and Transitory Trends

Constitution DAO, Woke Socialist Leadership, and Satya Nadella as Best CEO

Jack Dorsey, Brian Armstrong, and Frank Slootman as Best CEOs

Best Investor: Dan Loeb, Sequoia Fund, and Ken Griffin

Sequoia Fund and WeWork as Turnarounds

Disney's Streaming Success and Elizabeth Warren as Worst Human Being

McMichael, Bryan, Chauvin, and Daszak as Worst Human Beings

Best Meme and Most Loathsome Company

Tyson Foods, New York Times, and Meta as Most Loathsome Companies

Best New Tech: DAOs, Human Space Travel, and Substack

Starlink and Plasma Fusion as Best New Tech

Best Trend: Centrism, WokeLash, and the Creator Economy

Worst Trend: Entitlement, Supply Chain Decay, and Authoritarianism

The Metaverse as Worst Trend and Favorite Cultural Discoveries

Favorite Cultural Discoveries: San Francisco, Doja Cat, and Mimetic Theory

Loki, Yellowstone, and the Rudy Giuliani Award

Cuomo Brothers, Vaccine Claims, and Senator Karen as Self-Immolators

Biden's Disappointing Performance and Favorite Bestie

Reflections on the Podcast and Closing Remarks

E60: The 2021 Bestie Awards PLUS Jack Dorsey starts the Web3 Wars

All-In Podcast

00:00Introduction to the 2021 Bestie Awards

Introduction to the 2021 Bestie Awards

05:02Biggest Winner in Politics

Biggest Winner in Politics

08:01Joe Manchin's Impact and Biggest Loser in Politics

Joe Manchin's Impact and Biggest Loser in Politics

11:02The Progressive Left, Alt-Right, Kamala Harris, and Tony Fauci as Political Losers

The Progressive Left, Alt-Right, Kamala Harris, and Tony Fauci as Political Losers

14:36Biggest Political Surprise: Youngkin's Victory and Harris's Sideline

Biggest Political Surprise: Youngkin's Victory and Harris's Sideline

19:10Speculation on Kamala Harris's Future and Analysis of the Build Back Better Failure

Speculation on Kamala Harris's Future and Analysis of the Build Back Better Failure

22:24Biggest Winner and Loser in Business

Biggest Winner and Loser in Business

27:02Chinese Billionaires, Big Tech, and Meta as Business Losers

Chinese Billionaires, Big Tech, and Meta as Business Losers

30:51Biggest Business Surprise: Miami's Tech Boom and the Rise of DAOs

Biggest Business Surprise: Miami's Tech Boom and the Rise of DAOs

34:33Moderna/BioNTech and Oral COVID Antiviral Pills as Breakout Companies and Science Breakthroughs

Moderna/BioNTech and Oral COVID Antiviral Pills as Breakout Companies and Science Breakthroughs

37:34Concerns About Antiviral Side Effects and CRISPR Gene Editing

Concerns About Antiviral Side Effects and CRISPR Gene Editing

41:19SpaceX Starship and Transitory Trends

SpaceX Starship and Transitory Trends

44:40Constitution DAO, Woke Socialist Leadership, and Satya Nadella as Best CEO

Constitution DAO, Woke Socialist Leadership, and Satya Nadella as Best CEO

48:50Jack Dorsey, Brian Armstrong, and Frank Slootman as Best CEOs

Jack Dorsey, Brian Armstrong, and Frank Slootman as Best CEOs

52:43Best Investor: Dan Loeb, Sequoia Fund, and Ken Griffin

Best Investor: Dan Loeb, Sequoia Fund, and Ken Griffin

56:14Sequoia Fund and WeWork as Turnarounds

Sequoia Fund and WeWork as Turnarounds

1:00:07Disney's Streaming Success and Elizabeth Warren as Worst Human Being

Disney's Streaming Success and Elizabeth Warren as Worst Human Being

1:03:17McMichael, Bryan, Chauvin, and Daszak as Worst Human Beings

McMichael, Bryan, Chauvin, and Daszak as Worst Human Beings

1:07:14Best Meme and Most Loathsome Company

Best Meme and Most Loathsome Company

1:11:16Tyson Foods, New York Times, and Meta as Most Loathsome Companies

Tyson Foods, New York Times, and Meta as Most Loathsome Companies

1:14:45Best New Tech: DAOs, Human Space Travel, and Substack

Best New Tech: DAOs, Human Space Travel, and Substack

1:17:30Starlink and Plasma Fusion as Best New Tech

Starlink and Plasma Fusion as Best New Tech

1:20:23Best Trend: Centrism, WokeLash, and the Creator Economy

Best Trend: Centrism, WokeLash, and the Creator Economy

1:22:22Worst Trend: Entitlement, Supply Chain Decay, and Authoritarianism

Worst Trend: Entitlement, Supply Chain Decay, and Authoritarianism

1:25:07The Metaverse as Worst Trend and Favorite Cultural Discoveries

The Metaverse as Worst Trend and Favorite Cultural Discoveries

1:28:16Favorite Cultural Discoveries: San Francisco, Doja Cat, and Mimetic Theory

Favorite Cultural Discoveries: San Francisco, Doja Cat, and Mimetic Theory

1:31:22Loki, Yellowstone, and the Rudy Giuliani Award

Loki, Yellowstone, and the Rudy Giuliani Award

1:34:09Cuomo Brothers, Vaccine Claims, and Senator Karen as Self-Immolators

Cuomo Brothers, Vaccine Claims, and Senator Karen as Self-Immolators

1:37:23Biden's Disappointing Performance and Favorite Bestie

Biden's Disappointing Performance and Favorite Bestie

1:41:21Reflections on the Podcast and Closing Remarks

Reflections on the Podcast and Closing Remarks