The "All-In Podcast" episode features David Sacks, Chamath Palihapitiya, and Friedberg making predictions for 2022 across politics, business, and culture. Political predictions include Ron DeSantis as a big winner, potential conflicts involving Putin, and Xi Jinping's continued dominance, while Trump and the progressive left are seen as potential losers. Business forecasts highlight small businesses, Stripe's IPO, and the rise of the rest, while caution is advised for crypto projects lacking real-world applications and traditional payment systems like Visa and Mastercard. The discussion also covers contrarian beliefs, such as American influence soaring and the media flipping on COVID narratives, and addresses the impact of COVID policies on children, leading to a commitment to support school choice initiatives. Finally, they touch on best-performing assets like battery metals and early-stage startups, and anticipate trends like peer-to-peer payments in Africa and breakthroughs in biotech related to cell reprogramming.
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