Did you know every 40 seconds someone in the U.S. has a heart attack—and 1 in 5 never even see it coming? This week, I am joined by preventive cardiologist Dr. Michael Twyman as we discuss cutting-edge diagnostics, the endothelial glycocalyx, nitric oxide biology, and why muscle mass is your heart’s best friend. Learn the practical steps and questions to ask to protect your heart before symptoms appear.

Together, we explore:

Why silent heart attacks are so prevalent
The role of nitric oxide and the endothelial glycocalyx in vascular health
The critical link between muscle mass, VO₂ max, and heart resilience
How advanced imaging and testing are changing prevention
Debunking common myths around cardiovascular risk
Supplements and diagnostics Dr. Twyman uses to optimize cardiovascular health

This episode is a masterclass in heart disease prevention—don’t miss it.

Who is Dr. Michael Twyman

Dr. Twyman is a board-certified cardiologist specializing in early detection and prevention of cardiovascular disease. Founder of Apollo Cardiology in St. Louis, he’s recognized for integrating advanced arterial imaging, mitochondrial health strategies, and personalized medicine to optimize long-term heart health. Dr. Twyman’s mission is to educate his patients on how to live better and longer by optimizing their mitochondrial function to become heart attack proof.

This episode is brought to you by:

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Find Michael Twyman at:

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How to Prevent Heart Disease with Mitochondria, Muscle, and the Endothelial Glycocalyx | Dr. Michael Twyman

The Dr. Gabrielle Lyon Show