In episode 494 of The Genius Life, Max Lugavere interviews Dr. Nicholas Fabiano, a psychiatrist, about the intersection of exercise and mental health, the cognitive benefits of creatine, and the connection between ultra-processed foods, microplastics, and mental health decline. Dr. Fabiano shares his personal experiences and research, emphasizing the importance of exercise, diet, and lifestyle in treating depression and other mental health conditions. They discuss the role of inflammation, the potential overprescription of antidepressants, and the need for a more holistic approach to mental health treatment. The conversation also covers the types and intensity of exercise, the benefits of creatine for cognitive function, and the risks associated with microplastics in ultra-processed foods.