This podcast interviews the CEOs and CTOs of the Arc Institute and Vevo about the release of Tahoe-100, the largest single-cell drug-perturbed dataset ever created. The discussion covers the significance of this dataset for advancing AI in biology, the need for virtual cell models alongside protein structure prediction models, and the potential for accelerating drug discovery. A key takeaway is that Tahoe-100, with its 100 million data points, significantly increases the available data for training machine learning models in cellular biology, potentially leading to more accurate predictions of drug interactions with cells. The open-sourcing of this dataset aims to accelerate the field's progress by enabling broader collaboration and hypothesis-free research. The panelists discuss the potential for this data to revolutionize drug discovery by enabling the prediction of drug efficacy and the design of more effective treatments.