In this podcast episode, we explore exciting breakthroughs in neuroscience and gene editing, highlighting the game-changing roles of optogenetics and CRISPR technology. Zhang shares his journey from creating optogenetics, which uses light to manipulate neuronal behavior, to the landmark discovery of CRISPR as a precise gene-editing tool. The conversation touches on the history of CRISPR, its benefits compared to older methods, how it's used to treat genetic disorders, and the ethical issues surrounding germline editing. As the discussion unfolds, it underscores the need to balance innovation with responsibility, while offering a hopeful outlook on the future of science and education.