This podcast episode explores the concept of "Longshots" in the field of longevity research. Longshots are promising technologies that aim to improve human health and longevity but face significant challenges such as regulatory hurdles, hardware and software problems, and limited understanding of the aging process. The episode emphasizes the importance of understanding the role of lifestyle and choices in determining longevity and highlights the limitations of modern medicine in treating diseases rather than preventing them. It also discusses the potential of Longshots to delay the onset of chronic diseases and the role of AI technologies in advancing these innovations.