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Greg Isenberg · Business

The Startup Ideas Podcast

Get your creative juices flowing with The Startup Ideas Podcast. Published twice a week, we bring you free startup ideas to inspire your next venture. Hosted by Greg Isenberg, CEO of Late Checkout and former advisor to Reddit and TikTok. Subscribe so you don't miss out. For more startup ideas, we created a database of 30+ startup ideas you can take at https://gregisenberg.com/30startupideas

Episodes

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Graph Engineering Clearly Explained

03 Aug 2026
26m
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Jack Dorsey's Buzz: The New Hermes Agent?

28 Jul 2026
38m
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How I use Claude Code + MCPs to run my marketing

27 Jul 2026
37m
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How I run a team of AI Agents 24/7

24 Jul 2026
44m
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FDE: The $1M/Year AI Job Explained

20 Jul 2026
51m
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Forward Deployed Engineering (FDE) represents a critical bridge between general AI capabilities and specific business processes, shifting the competitive advantage from owning intelligence to effectively deploying it. FDEs function as a hybrid of technical experts and consultants, auditing business workflows to identif...

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The $1,000/hour Solo AI business (Full Course)

15 Jul 2026
1h 1m
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Small business owners often struggle to implement AI due to time constraints and technical barriers, creating a lucrative opportunity for consultants to provide "AI tools assessments." This model involves conducting a 45-minute discovery call to identify operational bottlenecks, followed by a report prescribing off-the...

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Making $$$ with Loop Engineering

13 Jul 2026
39m
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"Loop engineering" transforms business operations by leveraging AI agents to automate iterative processes, moving beyond simple task execution to continuous improvement. By establishing clear objective metrics—such as Google search rankings, ad profitability, or product performance evaluations—businesses can deploy age...

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Grok 4.5 is a bigger deal than Fable

10 Jul 2026
56m
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Grok 4.5 functions as a powerful, cost-efficient engine for autonomous AI agents, enabling them to act as genuine business co-founders. By integrating these models into platforms like Orgo and connecting them to essential tools—including email, phone, and browser interfaces—users can automate complex workflows that pre...

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We Tested OpenAI's GPT 5.6 for a Month

09 Jul 2026
49m
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AI Agents are the new SaaS

01 Jul 2026
26m
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“Learn AI” Is Bad Advice. Learn These Instead

25 Jun 2026
29m
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The agentic era demands a shift in skill sets to maintain professional relevance as AI automates traditional tasks. Success hinges on mastering six core competencies: managing AI agents and local models, executing deep distribution marketing, integrating robotics with AI, curating niche content through authentic storyt...

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GLM 5.2 Clearly Explained (and how to set it up)

23 Jun 2026
22m
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GLM 5.2 represents a significant inflection point for local AI, offering performance competitive with frontier models while remaining open-source and resource-efficient. By utilizing model chaining—or "fusion"—users can sequence tasks between high-reasoning models and execution-focused local models to optimize both qua...

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Making $$$ with IOS apps

15 Jun 2026
48m
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Claude Fable 5 is BANNED. What to do?

13 Jun 2026
24m
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You are using Claude Fable 5 wrong

11 Jun 2026
33m
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What are Agentic Loops?

09 Jun 2026
22m
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Agentic loops in AI development often suffer from excessive hype, frequently resulting in wasted token budgets and poor architectural decisions. While fully autonomous systems promise efficiency, they lack the nuanced human oversight required for complex product development, as AI agents inevitably make flawed assumpti...

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Become AI Native in less than 60 mins

08 Jun 2026
56m
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Becoming an AI-native organization requires a fundamental shift in operations, moving beyond simple tool usage to a system defined by people, agents, and context. People transition into managers of autonomous agents, focusing on strategy and judgment while AI handles execution. Success depends on creating an "agent-rea...

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Hermes Agent App Clearly Explained (and how to use it)

06 Jun 2026
43m
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The Hermes Desktop app transforms AI agent interaction by replacing fragmented CLI and messaging-based workflows with a centralized, visual interface. By leveraging distinct profiles for specific models—such as using Opus for strategy, GPT-5.5 for coding, and local models for research—users significantly reduce context...

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Codex Sites Clearly Explained (and how to use it)

04 Jun 2026
24m
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The Next $100B Market: Selling To AI Agents

02 Jun 2026
14m
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