a16z

The Brutal Truth About Biotech: Why $2B Per Drug Is Killing Innovation

Rocket Companies CEO: Here’s How to Fix the Housing Crisis

Grant Lee: Building Gamma’s AI Presentation Company to 100 Million Users

In this interview, Grant Lee, the co-founder of Gamma, discusses the company's journey from its inception in 2020 to becoming a successful AI application with over 100 million users and $100 million ARR. He shares early fundraising challenges, including a discouraging investor interaction, and how Gamma differentiated ...

Michael Truell: How Cursor Builds at the Speed of AI

Michael Truell, CEO of Cursor, discusses the company's origins, pivoting from a 3D mechanical engineering focus to AI-powered coding tools. He emphasizes Cursor's early focus on delivering a superior product within the VS Code ecosystem, the challenges of scaling rapidly with a small team, and the strategic decisions a...

Amjad Masad & Adam D’Angelo: How Far Are We From AGI?

Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease

The Chan Zuckerberg Initiative aims to accelerate the pace of basic science by developing shared, open-source tools that bridge the gap between frontier biology and artificial intelligence. By creating standardized datasets, such as the Cell Atlas, and building virtual cell models, the organization provides the scienti...

Seeing The Future from AI Companions to Personal Software

In this interview, Eugenia Kuyda discusses her career arc, from Replika to Wabi, emphasizing her focus on building AI-driven personal software to enhance daily life. She highlights the limitations of current chatbot interfaces, likening them to Microsoft DOS, and envisions a future where users can create and share mini...

ElevenLabs CEO: Why Voice is the Next AI Interface

Sacks, Andreessen & Horowitz: How America Wins the AI Race Against China

In this episode of the a16z podcast, David Sacks discusses AI and crypto policies, highlighting the differences in approach between the Trump and Biden administrations. For crypto, the focus is on regulatory clarity to encourage domestic growth, while for AI, the emphasis is on fostering innovation and competition, par...

Marc Andreessen and Ben Horowitz on the State of AI

Artificial intelligence models are rapidly approaching human-level capabilities in intelligence and creativity, yet their ultimate product form remains undefined, mirroring the historical evolution of personal computing from text-based prompts to graphical user interfaces. While concerns persist regarding the limitatio...

"Is there an AI bubble?” Gavin Baker and David George

David George from a16z interviews Gavin Baker, managing partner and CIO of Atreides, about the potential of an AI bubble. Baker argues against the existence of an AI bubble by comparing it to the internet bubble of 2000, highlighting the key difference of "dark fiber" versus the full utilization of GPUs today. They dis...

Building the Real-World Infrastructure for AI, with Google, Cisco & a16z

The podcast features Raghu Raghuram moderating a discussion between Amin Vahdat and Jeetu Patel about the current infrastructure cycle, comparing it to the internet boom but noting its unprecedented scale due to geopolitical, economic, and national security implications. They explore the demand for compute, networking,...

Google DeepMind Developers: How Nano Banana Was Made

The podcast features a discussion about the Nano Banana model, its development, capabilities, and potential impact on creative arts and education. The speakers share insights on the model's origin, its unique features like character consistency and interleaved generation, and its applications in various fields. They ex...

Marc Andreessen: How Movies Explain America

Marc Andreessen & Amjad Masad on “Good Enough” AI, AGI, and the End of Coding

This podcast features an interview with Amjad Masad, the founder of Replit, who discusses the evolution and future of AI in coding. Masad explains how Replit utilizes AI agents to assist both novice and experienced programmers in building applications using natural language. The conversation covers the technical breakt...

Why Creativity Will Matter More Than Code | Kevin Rose and Anish Acharya

How Kong Was Born: APIs, Hustle, and the Future of AI Infrastructure

This podcast features an interview with Augie, the founder and CEO of Kong, formerly MashApe, detailing his journey from a Milan garage to leading a company with IPO ambitions. Augie recounts the early struggles, including living illegally in the U.S. on minimal funds, sleeping on couches, and the pivotal moments that ...

Reid Hoffman on AI, Consciousness, and the Future of Labor

The a16z podcast features Reid Hoffman, a successful Web2 investor, discussing his frameworks for AI investing. He outlines three key areas: obvious AI applications like chatbots and coding assistance, identifying traditional elements that remain relevant despite disruption, and exploring Silicon Valley blind spots, pa...

Marc Andreessen on the State of Film and Hollywood

Keith Rabois: Israel, OpenAI, Opendoor, and DOGE