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Nick Jikomes · Health

Mind & Matter

Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists & thinkers alive today about how your mind-body reacts to what you feed it. The weekly M&M podcast features conversations with the most interesting scientists, thinkers, and technology entrepreneurs alive today. Not medical advice. At M&M, we are interested in trying to figure out how things work, not affirming our existing beliefs. We prefer consulting primary rather than secondary sources and independent rather than institutional voices. If we encounter uncomfortable truths or the evidence suggests unfashionable ideas may be valid, so be it. As the host, my aim is to help you better understand how the body & mind work by curating & synthesizing information in a way that yields science-based insights that you can choose to use or disregard in your own life. Taking ownership of your health starts with taking ownership of your information diet. I am motivated to connect the dots and distill general principles from what I learn, preferring to ask questions and play devil’s advocate to debating or incessantly pushing my own viewpoint. My beliefs: Taking ownership of your health starts with taking ownership of your information diet . All knowledge is provisional and we must work hard to prevent ourselves from becoming attached to our favorite ideas & preferred conclusions. Wisdom comes from an iterative, trial-and-error process of learning and unlearning. Letting go of pre-conceived notions can be painful, but pain is information. Sometimes modern discoveries teach us we must unlearn received wisdom. Other times, modern information overload & historical chauvinism cause us to forget ancient wisdom which stills applies. The framework for learning that I embody is inspired by three Ancient Greek maxims inscribed in the Temple of Apollo at Delphi: “Γνῶθι σεαυτόν” ( Know thyself ) “Μηδὲν ἄγαν” ( Nothing in excess) “Ἐγγύα πάρα δ Ἄτα” ( Certainty brings insanity)

Episodes

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SSRIs, Sexual Dysfunction, Suicide & Mass Shootings, How FDA Works | David Healy | 232

05 Jun 2025
2h 10m
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Psychedelic Chemistry, Magic Mushrooms, Kratom, Gray Market Research Chemicals, Vape Shops | Andrew Chadeayne | 231

25 May 2025
1h 38m
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Psilocybin & MDMA: Inflammation, Stress & Brain-Body Communication | Michael Wheeler | 230

20 May 2025
1h 9m
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Linoleic Acid, Seed Oils, mTOR & Breast Cancer | Nikos Koundouros & John Blenis | 229

15 May 2025
1h 47m
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Rhythms, Memory, Time, Place, Representation & the Brain | György Buzsáki | 228

10 May 2025
1h 48m
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Biophysics of Life: Biophotons, Light, Quantum Biology, Regeneration & Cancer | Nirosha Murugan | 227

05 May 2025
1h 39m
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Psychedelics & Cerebral Cortex: Neuroplasticity, Psilocybin, Ketamine | Alex Kwan | 226

01 May 2025
1h 17m
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Nutrition Epidemiology: Fake Science? | John Speakman | 225

26 Apr 2025
1h 5m
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Cancer Biology: Metabolism, Mitochondria & Energy | Thomas Seyfried | 224

23 Apr 2025
1h 52m
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Ketogenic Diet: Cholesterol, Plaque & Heart Heart | Matthew Budoff | 223

19 Apr 2025
58m
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Genetics & Neurobiology of Obesity: Hypothalamus, Leptin, Gut Hormones, Weight Loss Drugs | Giles Yeo | 222

15 Apr 2025
1h 33m
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Regenerative Energy & the Light Inside You | Jack Kruse | 221

11 Apr 2025
2h 26m
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Cell Death, Oxidative Stress, PUFAs & Antioxidants | Pamela Maher | 220

08 Apr 2025
1h 40m
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Shamanism, Human Culture & the Evolution of Religion | Manvir Singh | 219

04 Apr 2025
1h 44m
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Chemical Exposures, Neurodegenerative Disease & Exposomics | Gary Miller | 218

31 Mar 2025
1h 33m
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Communication & Social Cognition in Elephants & Animals | Mickey Pardo | 217

27 Mar 2025
1h 39m
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Can Aspirin Prevent Cancer Metastasis? | Rahul Roychoudhuri | 216

23 Mar 2025
1h 26m
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Cancer Metabolism: Sugar, Fructose, Lipids & Fasting | Gary Patti | 215

19 Mar 2025
1h 45m
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Gut Microbiome Plasticity | Peter Turnbaugh | 214

14 Mar 2025
41m
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Causes of Diabetes: Insulin, Mitochondria, Genetics, Metabolism | Scott Soleimanpour | 213

10 Mar 2025
49m
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