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WaitWhat · Business

Masters of Scale

On Masters of Scale, iconic business leaders share lessons and strategies that have helped them grow the world's most fascinating companies. Founders, CEOs, and dynamic innovators join candid conversations about their triumphs and challenges with a set of luminary hosts, including founding host Reid Hoffman (LinkedIn co-founder and Greylock partner). From navigating early prototypes to expanding brands globally, Masters of Scale provides priceless insights to help anyone grow their dream enterprise.

Episodes

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GaryVee on how to make Super Bowl ads that are actually funny

07 Feb 2026
12m
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The discussion centers on the evolving landscape of marketing and advertising, particularly regarding social media and AI. Gary Vaynerchuk (Gary Vee) shares his insights on a Raisin Bran Super Bowl ad and the strategic thinking behind leveraging social media to amplify its impact by tailoring messages to different demo...

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How Zoom grew 30x almost overnight

05 Feb 2026
27m
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The discussion centers on Eric Yuan's journey, from his early career at WebEx to founding Zoom. Yuan recounts his initial struggles to obtain a visa to Silicon Valley and his motivations for leaving Cisco to create a better video conferencing solution. A key element of Zoom's success, according to Yuan, is the company ...

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Padma Lakshmi’s secret to authentic leadership? Stop trying.

03 Feb 2026
29m
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Padma Lakshmi, TV host, author, producer, and U.N. goodwill ambassador, discusses her new show, "America's Culinary Cup," and the intersection of food, culture, and politics. Lakshmi aimed to create a culinary institution focused on the pursuit of excellence, providing chefs with top-tier resources and judging them on ...

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Possible: Amjad Masad on vibe coding, AI agents, and the end of boilerplate

31 Jan 2026
1h 16m
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The conversation centers on the transformative power of AI and no-code platforms, particularly Repl.it, in democratizing software creation. Amjad Masad, founder and CEO of Repl.it, discusses how the platform enables individuals, including CEOs and those without coding backgrounds, to bring their ideas to life. He draws...

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How to break through a fear of failure, with Fawn Weaver & Van Jones

29 Jan 2026
22m
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Fawn Weaver, founder of Uncle Nearest Premium Whiskey, discusses building a billion-dollar spirits business and prioritizing an extraordinary life over solely focusing on profit and loss. Weaver emphasizes the importance of love, both self-love and love from others, as a crucial element for success and resilience in th...

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Reid Hoffman on AI’s new tune, Davos, and the need for CEO courage

27 Jan 2026
37m
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Reid Hoffman and Bob Safian discuss AI's transformative potential and the challenges of navigating its development. Hoffman argues AI is a powerful tool for enhancing human quality of life, referencing his AI-generated Christmas music album as an example of AI's creative applications. He cautions against unproductive c...

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Reid Hoffman & Inflection AI’s Sean White on designing AI that makes us better humans

24 Jan 2026
21m
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The discussion centers on the evolving relationship between humans and AI, particularly the importance of designing AI agents that enhance human connection rather than replace it. Reid Hoffman and Sean White explore the need for transparency in AI interactions, ensuring users recognize they are engaging with a non-sent...

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How to make smarter changes, with cognitive scientist Maya Shankar

22 Jan 2026
34m
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The podcast explores the theme of navigating significant life changes, emphasizing that such changes often lead to personal growth. Cognitive scientist Maya Shankar, author of "The Other Side of Change," shares her experience of losing her career as a concert violinist at age 15 due to an injury and how she redefined h...

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Anti-polarizing strategies from a purple city, with OKC Mayor David Holt

20 Jan 2026
31m
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Oklahoma City's transformation from a struggling city to the 20th largest in the U.S. is attributed to strategic investments in quality of life, initiated after failing to secure a United Airlines facility in the early 90s. Mayor David Holt emphasizes the importance of a strong business community and controlled immigra...

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How to save a magazine, with The Atlantic’s Nicholas Thompson

15 Jan 2026
37m
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Nick Thompson, CEO of The Atlantic, discusses the strategies behind the magazine's turnaround, emphasizing the importance of a robust digital subscription model and data-driven testing of paywall variables. Thompson shares how The Atlantic shifted from losing millions to profitability by implementing a sophisticated pa...

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The AI agents in your wallet, with Mastercard CEO Michael Miebach

13 Jan 2026
24m
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MasterCard CEO Michael Miebach discusses consumer spending trends, the impact of AI on financial security, and the future of payment technologies. Analyzing data from 160 billion transactions, Miebach notes a 3.9% increase in holiday spending, driven by apparel sales and early-season promotions, with real volume increa...

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How Baby2Baby stepped up as LA wildfires raged

10 Jan 2026
37m
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Baby2Baby's co-CEOs, Norah Weinstein and Kelly Sawyer Patricof, discuss scaling their nonprofit, which provides essential resources to children in need. Starting from a small office, they identified a critical gap: the lack of access to diapers for low-income families. They share how a serendipitous event involving cel...

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The $800M exit that started with a single muffin

08 Jan 2026
32m
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Katlin Smith, founder of Simple Mills, discusses building a better-for-you brand. Smith recounts her journey from experimenting with recipes in her apartment to selling Simple Mills for nearly $800 million. Her motivation stemmed from personal dietary changes, leading her to create nutrient-dense baking mixes using unc...

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Business world predictions for 2026

06 Jan 2026
27m
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Bob Safian discusses his predictions for 2026 with Alex Morris, focusing on potential shifts in technology, economics, and societal trends. He anticipates a stall in tech stocks due to unmet AI value expectations and suggests AI may be used as a justification for layoffs. Safian also forecasts a crisis level in cyber h...

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The science of fresh starts

01 Jan 2026
33m
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In this episode of Masters of Scale, host Jeff Berman interviews Katy Milkman, a behavioral scientist and author of "How to Change," about strategies for achieving personal and organizational goals. Milkman discusses the concept of "fresh starts" and their temporary motivational boost, emphasizing the importance of und...

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Pioneers of AI: Mark Cuban’s investment strategy in this new era of tech

30 Dec 2025
40m
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In this episode of Pioneers of AI, Rana El Kaliouby interviews Mark Cuban about his views on AI, ranging from its impact on media, marketing, and healthcare to investment strategies. Cuban shares his experiences with AI tools like Sora and Synthesia, and discusses the potential of AI in preventative medicine, entrepren...

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How to unlock your team’s creative potential

25 Dec 2025
33m
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This episode of Masters of Scale features Reid Hoffman interviewing Indra Nooyi, the former CEO of PepsiCo, about creating an environment where talent can thrive. Nooyi shares her personal experiences and insights, from her upbringing in India to her career at Johnson & Johnson and PepsiCo, emphasizing the importance o...

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Resurrecting dire wolves is just the beginning for Colossal Biosciences’ Ben Lamm

23 Dec 2025
33m
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Bob Safian interviews Ben Lamm, the CEO of Colossal Biosciences, about the company's work on de-extinction, specifically focusing on the resurrection of the dire wolf. Lamm explains the science behind their work, which involves tweaking the DNA of existing gray wolves to match that of ancient dire wolves, addressing co...

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The Salesforce CFO who left to save lives

18 Dec 2025
39m
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Jeff Berman interviews Amy Weaver, former CFO of Salesforce and current CEO of Direct Relief, about her nonlinear career path and her transition from the corporate world to leading a humanitarian organization. Amy discusses her early aspirations, her experiences at Expedia and Salesforce, the challenges she faced, and ...

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Lessons of Rapid Response for 2026

16 Dec 2025
24m
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This special episode of Rapid Response presents five key lessons for navigating business and career challenges in an era of rapid disruption, drawing from the experiences of leaders in various fields. The lessons emphasize the need for agility in the face of technological advancements like AI, the importance of human c...

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