This Week in Startups · Business

This Week in Startups

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators. If you want to ask a question about your career, your startup or angel investing email [email protected]. Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Follow Jason: https://linktr.ee/calacanis Follow This Week in Startups on Twitter: https://twitter.com/TWiStartups Subscribe to TWiST Clips for the BEST moments: https://www.youtube.com/channel/UCS7tJlcUA6PzVHEMo-X7ddg?sub_confirmation=1

Episodes

The Drone Company worth $4B+ (Keller Clifton), and How Rahul Vohra Built Superhuman | E2265

20 Mar 2026

1h 37m

AI processed

Building transformative technology requires solving critical, high-stakes problems and maintaining a long-term vision despite initial skepticism. Zipline’s automated logistics system succeeded by first addressing life-saving medical deliveries in Rwanda, proving reliability before scaling to commercial markets like Dal...

Decentralized AI networks, specifically Bittensor (TAO), are revolutionizing infrastructure by incentivizing developers to build cost-effective, specialized AI products through a competitive subnet model. This "age of excellence" allows for efficient, permissionless innovation in fields like coding assistance, video co...