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Y Combinator · Business

Y Combinator

Episodes

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Agency and Independence

10 Sep 2025
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The FDE Playbook for AI Startups with Bob McGrew

08 Sep 2025AI processed

In this episode of The Light Comb, Bob McGrew, formerly Chief Research Officer at OpenAI and an early executive at Palantir, discusses the Forward Deployed Engineer (FDE) model, which originated at Palantir and is now gaining traction among AI agent startups. McGrew explains that an FDE is an engineer who works at the ...

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Michael Truell: Building Cursor at 23, Taking on GitHub Copilot, and Advice to Engineering Students

03 Sep 2025AI processed

Michael Truell, co-founder of Cursor, details the evolution of his company from a series of failed experimental projects to a leading AI-powered code editor. After early attempts to build AI tools for mechanical engineers and secure messaging, the team recognized a fundamental shift in software development, leading the...

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GPT-OSS vs. Qwen vs. Deepseek: Comparing Open Source LLM Architectures

29 Aug 2025
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AI won’t make coding obsolete. It will make it universal.

28 Aug 2025
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How This 25-Year-Old Built A $675M Legal AI Startup (With No Legal Experience)

26 Aug 2025
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Technical Expertise is Now the Missing Piece

22 Aug 2025
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Intellectual Fearlessness

20 Aug 2025
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Anthropic Co-founder: Building Claude Code, Lessons From GPT-3 & LLM System Design

19 Aug 2025AI processed

In this episode of The Light Cone, Tom Brown, co-founder of Anthropic, discusses his journey from MIT to co-founding Anthropic. He shares his early career experiences at startups like LinkedLanguage and Mopo, his transition into AI research at OpenAI, and the events leading to the creation of Anthropic. Brown also disc...

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The Sales Playbook For Founders | Startup School

15 Aug 2025
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Satya Nadella on Leadership

11 Aug 2025
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Dylan Field: Scaling Figma and the Future of Design

08 Aug 2025
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Where does your interest come from?

05 Aug 2025
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Using LLMs Instead of Government Consulting

03 Aug 2025
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AI Native Enterprise Software

02 Aug 2025
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Infrastructure for Multi-Agent Systems

01 Aug 2025
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The First 10-person, $100B Company

01 Aug 2025AI processed

The speaker discusses how new AI tools are enabling small, high-agency teams and even solo founders to build multi-billion dollar companies with significantly less capital, drawing a parallel to the impact of cloud computing 15 years ago. They emphasize that future successful startups will optimize for "Revenue per emp...

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The Finance Startup Bringing Agentic AI to Wall Street

31 Jul 2025
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Video Generation as a Primitive

31 Jul 2025
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Retraining Workers for the AI Economy

30 Jul 2025
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