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Steve Hsu · Science

Manifold

Steve Hsu is Professor of Theoretical Physics and Computational Mathematics, Science, and Engineering at Michigan State University. Join him for wide-ranging conversations with leading writers, scientists, technologists, academics, entrepreneurs, investors, and more.

Episodes

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Polygenics and Machine SuperIntelligence; Billionaires, Philo-semitism, and Chosen Embryos – #102

01 Jan 2026
1h 0m
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In this year-end episode of Manifold for 2025, Steve Hsu discusses advancements in two scientific areas: polygenic prediction and embryo selection, and artificial intelligence. Regarding genomics, Hsu highlights a study validating polygenic risk scores for breast cancer screening and a breakthrough in polygenic predict...

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Theoretical Physics With Generative AI – #101

18 Dec 2025
1h 12m
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Jeffrey Epstein, Israel, and Elite Power, with Murtaza Hussain – #100

04 Dec 2025
1h 3m
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Jian Lian on China's Industrial Policy and Global Strategy – #99

20 Nov 2025
1h 12m
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In this episode of Manifold, Steve Hsu interviews John Lian, a policy analyst from Beijing, about the Chinese development model and the competition between the U.S. and China. Lian discusses his early life and education, including his experience with the Chinese university entrance examination and his initial interest ...

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Scott Horton on the Russia Hoax and Ukraine War – #98

06 Nov 2025
1h 25m
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In this episode of Manifold, Steve Hsu interviews Scott Horton, director of the Libertarian Institute and editorial director of Antiwar.com, about Russiagate and the lead-up to the Ukraine War. Horton argues that the CIA, FBI, and Democrats framed Donald Trump for treason, detailing the false accusations and the roles ...

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AIs Win Math Olympiad Gold: Prof. Lin Yang (UCLA) – #97

23 Oct 2025
50m
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The Global AI Race: Z.ai and the View from Beijing — #96

09 Oct 2025
1h 6m
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Seeking Truth From Facts: Weeks Where Decades Happen — #95

25 Sep 2025
48m
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Kyle Chan on the Future of US-China Competition — #94

11 Sep 2025
1h 10m
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In this episode of Manifold, Steve Hsu interviews Kyle Chan, a postdoctoral researcher at Princeton University, about US-China technology competition, AI, globalization, and multipolarity. They delve into Chan's intellectual journey from economics to sociology, focusing on his dissertation work comparing railway develo...

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Joleen Liang: 40M+ kids educated by adaptive AI — #93

28 Aug 2025
59m
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Max Dama on HFT: Millisecond Algos and Bid/Ask Dynamics — #92

14 Aug 2025
54m
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In this episode of the Manifold podcast, Steve Hsu interviews Max Dahmer, co-chair of Headlands Technology, a quant prop trading firm. Dahmer discusses his background, from his early interest in AI and trading to his education at Berkeley, where he pursued multiple degrees and founded a trading club. He shares insights...

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Andrew Song: Global Cooling with Sulfur Dioxide in the Stratosphere — #91

31 Jul 2025
1h 4m
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In this episode of Manifold, Steve Hsu interviews Andrew Song, a founder of Make Sunsets, a climate startup. Andrew discusses his background, including his time as a competitive swimmer and his initial career in economic consulting. He shares the inspiration behind Make Sunsets, which aims to cool the Earth by launchin...

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Manifold Discord Channel: Live Q&A with Steve — #90

17 Jul 2025
54m
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In this inaugural Manifold Live Q&A, hosted on Discord, Steve Hsu addresses questions from listeners on a range of topics. He begins by outlining his vision for genomics research, advocating for a large-scale data set linking genomes with psychometric scores to predict cognitive ability. Hsu then discusses his involvem...

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Omar Shams: AI Founder and Google AI Agent Lead — #89

03 Jul 2025
1h 5m
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In this episode of Manifold, Steve Hsu interviews Omar Shams, an AI founder recently acquired by Google and now a lead on AI software agents. They discuss Omar's background in theoretical physics, his transition to AI, and his experiences as a startup founder. The conversation covers the AI race, the importance of ener...

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Patrick McGee: Apple In China — #88

19 Jun 2025
59m
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In this episode of Manifold, Steve Hsu interviews Patrick McGee, author of "Apple in China," about the intricate relationship between Apple and China's manufacturing capabilities. McGee details how Apple's partnership with Foxconn, and later other Chinese suppliers, facilitated the production of beautifully designed pr...

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GODZILLA IS DOWN! India-Pakistan Clash and Chinese Military Technology with TP Huang — #87

05 Jun 2025
1h 2m
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Robots, Small Models, and RL with DeepSeek Alumnus Zihan Wang — #86

22 May 2025
1h 7m
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Dan Collins: Tariffs and the Future of US Manufacturing — #85

08 May 2025
1h 18m
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Seeking Truth From Facts: AI, China, Tariffs, Geopolitics — #84

24 Apr 2025
45m
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Incels, Evo Psych, and Modern Literature with ARX-Han

10 Apr 2025
1h 25m
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