Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down with their personal functional medicine doctor and longtime friend, Dr. Scott Collie, for a deep dive into blood work, cardiovascular health, gut health, thyroid, and what actually matters when you are running gear or peptides.

Chapters:

00:00 – Intro: Dr. Scott & Talking Real Food (Italy Recap)

05:29 – The Truth About "Running Gear"

06:15 – TRT vs. Steroid Cycles Explained

10:22 – Why Bloodwork Timing Matters On vs. Off Cycle

12:58 – Blood Sugar, Insulin & GLP-1s

17:45 – Kidney, Liver & Iron Health Markers

22:25 – Understanding Cholesterol: LDL, HDL & VLDL

27:31 – Thyroid Health & Hashimoto's

30:06 – Homocysteine & Methylation

35:13 – Rapid Weight Loss & Gallbladder Risks

39:16 – Inflammatory Markers & Heart Damage Warning Signs

46:02 – Top Supplements & Peptides for Cycle Support

53:41 – Cycle Timing & When to Test Blood

1:01:51 – Hydration & Final Thoughts

1:06:07 – Outro & Where to Find Dr. Scott

We cover:

🩺What functional medicine actually looks at

– Standard doctor panels are a snapshot, not a full picture

– Dr. Scott runs up to 75 markers including cardiovascular, inflammatory, kidney, thyroid, and gut markers

– Most insurance doctors stop at LDL and HDL, missing the full story completely

– You need particle size, not just cholesterol weight, to understand your true cardiovascular risk

🫀 Cardiovascular markers that matter

– APOB: umbrella marker for all arteriosclerotic particles including VLDL, LDL, and IDL

– Particle size is critical: anabolic steroids shift particles to small dense LDL, the type that sticks and clogs arteries

– Myeloperoxidase and LP-PLA2: direct markers of vascular inflammation most doctors never run

– Triglycerides plus elevated liver enzymes (AST/ALT) almost always means fatty liver, no ultrasound needed

– Fibrinogen: a clotting protein made by the liver, high fibrinogen plus high insulin plus high triglycerides is a walking time bomb, especially for steroid users

– CRP (C-Reactive Protein): one of the best inflammatory markers available, if it is high something serious is going on

🧬Homocysteine, the underrated killer

– Homocysteine scars the inside of your arteries so plaque particles can park and stick

– Now being studied as an Alzheimer's marker as well

– Dr. Scott wants it at 7 or below, many people are at 9 to 50

– Fix: methylate with B6, B12, and methyl folate, simple and cheap

– TRT alone will elevate homocysteine, so methylating is a must for anyone on testosterone

⚖️Retatrutide and rapid fat loss, what to watch

– Losing fat very fast can back up bile flow and cause gallstones, not kidney stones

– Check alkaline phosphatase and GGT before starting Reta if there is any gallbladder history

– Signs of gallbladder issues: bloating, belching, pain under right rib cage, high-fat meal distress, floating stools

– Floating poop is not a good sign, it means fat is not being absorbed properly

– Blood sugar, triglycerides, and inflammatory markers improve dramatically and quickly on Reta

🩸Blood work timing for gear users

– Best time to test: before the cycle starts, to establish your baseline

– After the cycle ends: retest to confirm you returned to baseline

– Mid-cycle testing will look alarming by design, be ready for that

– If you do not know what different esters are, you are not ready to run gear

Follow Dr. Scott Collie:

Website: https://heydrscott.com/

Facebook: https://www.facebook.com/DrScottCollie/

Instagram: https://www.instagram.com/hey_dr_scott/

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Peptide of the Week: Blood Work, Gut Health & Gear – With Dr. Scott Collie

Peptide of the Week | Weight Loss, Health & Wellness

Peptide of the Week: Blood Work, Gut Health & Gear – With Dr. Scott Collie