Best of Big Technology: How Ozempic Changes Our Bodies, Minds, and Economy — With Johann Hari

GLP-1 agonists like Ozempic are fundamentally altering human physiology and the global economy by artificially inducing satiety. These drugs address an obesity crisis driven by the proliferation of ultra-processed foods, which have systematically undermined natural appetite regulation. Johann Hari, author of *Magic Pill*, explains how these medications lower biological set points, potentially reversing chronic conditions like heart disease and diabetes. However, the rapid adoption of these drugs creates significant friction between the pharmaceutical industry and food corporations, whose business models rely on high-volume consumption. Beyond physical benefits, concerns remain regarding long-term metabolic impacts, potential emotional blunting, and the ethical implications of prescribing these treatments to children. Ultimately, these drugs represent a profound shift in how society manages health, mirroring the transformative, yet unpredictable, impact of the smartphone on modern life.