What has been the cost to women of relying on research that was never designed around female physiology?

Dr. Stacy Sims is an exercise physiologist, nutrition scientist, and bestselling author of ROAR, which challenged the idea that women should train and fuel like men, and Next Level, which focuses on health, performance, and physiology through perimenopause and menopause. Over two decades of research, she has become one of the leading voices reshaping how we understand women's health, with a message that has become synonymous with her work: women are not small men. That line started as a throwaway teaching point during her postdoc at Stanford, and it has since become a paradigm shift.

At the center of this conversation is a quiet, costly problem. For decades, much of the science on training, nutrition, and medicine was built on male bodies and then applied to women as if they were simply smaller versions of men. Stacy walks through what that gap has cost, why the literature thins out for women between the ages of thirty and fifty, and how a hormone fluctuation can get mistaken for a panic attack, leading to solutions that were never going to fully work.

Stacy and Mike then move into what to actually do about it. They get into why "eat less, train more" often backfires and drives the body into a low energy state, why fasting through the morning for women can dysregulate appetite and stress hormones, and why lifting heavier loads may protect not just muscle and bone but the aging brain. They also draw the line that runs through the whole conversation, the symptoms of perimenopause are the physiology, not the person, and explore why this episode isn't just for the women in the community. Stacy explains why having men in the conversation helps drive action, what partners can actually do... listen first rather than rush to fix... and why the rising noise around menopause online, along with AI tools built on outdated male data, makes clear thinking here more valuable than ever.

In this conversation, we explore:

Why so much health and performance research was never actually done on women
What "women are not small men" really means in training and nutrition
Why "eat less, train more" often backfires for women through midlife
Why fasting through the morning can dysregulate appetite and stress hormones
How lifting heavier loads may help protect the aging brain
Why men belong in this conversation, and how to show up for the women in their lives
Why most AI health tools still run on outdated male data

Whether this conversation is about your body or the body of someone you love, it offers a science-backed way to understand what's happening and what to do next.

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Dr. Stacy Sims’ Books: ROAR and Next Level

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Women Are Not Small Men | Dr Stacy Sims

Finding Mastery with Dr. Michael Gervais

Women Are Not Small Men | Dr Stacy Sims