Cardiologist Dr. Peter McCullough on mRNA Persistence, Nattokinase, and the Fight Over COVID-19 Treatment"

Six years after standing before the US Senate and calling out the pandemic response in real time, Dr. Peter McCullough returns with new evidence on where the spike protein came from, how long it persists in the body after infection or vaccination, and what's being done to break it down. This episode traces the science from a 2015 gain-of-function paper to a patient still showing circulating spike protein 3.6 years after vaccination.

Get Dr. McCullough's free spike protein guide: myfreespikeguide.com

Host Dave Asprey sits down with Dr. Peter McCullough, a physician trained in internal medicine, cardiology, and epidemiology, and one of the most published and most censored voices of the COVID-19 pandemic. He authored the first multi-drug treatment protocol for COVID-19, testified before the US Senate in 2020 and again in 2025, and has published extensively in the peer-reviewed literature on vaccine safety, spike protein biology, and early treatment. His book Courage to Face COVID-19 and his most recent New York Times bestseller, Vaccines, Mythology, Ideology and Reality, examine the history and science behind vaccine policy.

Dave and Dr. McCullough trace the origins of the spike protein back to 2015 and 2016 research papers describing a lab-created, SARS-like coronavirus explicitly labeled "poised for human emergence," and discuss the funding, institutions, and researchers involved. They break down why synthetic mRNA vaccines resist the body's normal RNA breakdown process, what a patient case revealed about spike protein circulating 3.6 years after vaccination, and how nattokinase, a natural enzyme, has shown the ability to break the spike protein down. They also cover the suppression campaigns against ivermectin and hydroxychloroquine, the wartime propaganda origins of terms like "misinformation" and "anti-vaxxer," and what Dr. McCullough says he would do differently if he ran HHS. The conversation closes with new research on cognitive superagers, the small percentage of people who reach 100 with intact memory and health.

You'll Learn:

Why 2015 and 2016 research papers described a lab-created coronavirus as "poised for human emergence" years before the pandemic
Why synthetic mRNA in COVID-19 vaccines resists the body's natural RNA breakdown process
What one patient's case revealed about spike protein still circulating 3.6 years after vaccination
How nattokinase, a natural enzyme, has been shown to break down the spike protein
Why the FDA and FTC targeted ivermectin, hydroxychloroquine, and companies selling nasal sprays during the pandemic
The wartime propaganda origins of terms like "misinformation," "disinformation," and "anti-vaxxer"
What Dr. McCullough says he would do first if he were running HHS
What research on cognitive superagers reveals about the small number of people who reach 100 with intact health

Thank you to our sponsors!

- TrueDark | Visit truedark.com and use code DAVEASPREY15 (discount applies to all frames except Aegis)

- ZenBud | Dave’s Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount.

- Qualia | Go to qualialife.com/ASPREY for 50% off, and use code ASPREY for an additional 15% off.

- ENERGYbits | If you want a simpler, smarter way to support your body… this is it. Head to ENERGYbits.com and use code ASPREY for 20% off your order.

Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.

New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.

Keywords: spike protein detox, how long does spike protein last in your body, nattokinase spike protein, mRNA vaccine side effects, is the spike protein still in my blood, gain of function research explained, where did COVID come from, Wuhan lab leak evidence, ivermectin banned, why was hydroxychloroquine banned, vaccine injury compensation act, mRNA vaccine shedding, spike protein detox protocol, how to live to 100, cognitive superagers, Peter McCullough, Dave Asprey

Resources:

• Learn More About Dr. McCullough’s Work At: https://www.twc.health/pages/focal-points

• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/

• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.

• Danger Coffee: https://dangercoffee.com/discount/dave15?

• My Daily Supplements: SuppGrade Labs (15% Off)

• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)

• Dave Asprey’s BEYOND Conference: https://beyondconference.com

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/

• Upgrade Labs: https://upgradelabs.com

Timestamps:

00:00 – Trailer

00:43 – Intro

02:10 – 2020 Public Health Failures

05:07 – Vaccine History & Mythology

07:19 – Vaccine Hesitancy as Disease

13:12 – Masks & Lockdown Absurdity

18:03 – War on Hydroxychloroquine

23:56 – Ivermectin Suppression

28:58 – FTC Misinformation Crackdown

31:18 – Propaganda Terms Explained

39:55 – McCullough's Confidence & Career

43:08 – Spike Protein Origins

57:10 – Nattokinase & Spike Clearance

58:50 – mRNA Persistence in Body

1:11:50 – Fixing the System

1:17:32 – Political Divisiveness

1:22:41 – Secrets to Longevity

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Peter McCullough: Spike Protein Detected 3.6 Years After the Shot (Detox Protocol) : 1501

The Human Upgrade: Biohacking for Longevity & Performance

Peter McCullough: Spike Protein Detected 3.6 Years After the Shot (Detox Protocol) : 1501