Jacob Kimmel returns to the show. And he might have cured the hangover and liver disease. NBD.

Kimmel is the co-founder and president of NewLimit and one of the deepest thinkers in the longevity field. His company has been working to reverse the aging process in the body and has seen some stunning results with a new therapy that undoes liver damage in mice. We’re talking old mice that shrug off the effects of too much booze as if they were teenagers and that exhibit recoveries from long-term alcohol abuse.

The results have been good enough to help NewLimit raise another $435 million from the likes of Founders Fund and Thrive Capital. They’re also good enough to have NewLimit kick off a human trial of the therapy next year. And I’ll drink to that.

We discuss all of this on the podcast and then go much deeper on the longevity field, bio-tech and the collision of AI and biology.

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Timestamps

0:0) Intro3:50 What Is Epigenetic Reprogramming?7:16 Growing a Whole Animal From One Old Cell13:06 Meet Ambrosia, the AI Hunting for Youth22:44 $435 Million and the Race to Human Trials29:26 The Drunk Mice That Skip the Hangover36:48 Inside the First Human Trial43:14 Will There Ever Be a Hangover Pen?49:39 Beyond the Liver: The Delivery Problem1:03:27 Answering the Skeptics1:12:42 Will OpenAI Become a Drug Company?1:23:53 The Health Story Bigger Than AI?1:35:00 How Far Behind Is the US vs China?1:53:10 Can We Build Computers From Neurons?

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Can You Reverse Decades of Drinking Damage? Perhaps. - EP 75 Jacob Kimmel Is Back

Core Memory

Can You Reverse Decades of Drinking Damage? Perhaps. - EP 75 Jacob Kimmel Is Back