01 Jun 2026
40m

D-Dimer for Dissection and Evidence Update with Dr. Lauren Westafer

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ACEP Frontline

Emergency medicine practice is evolving through updated guidelines on diagnostic testing and therapeutic interventions. Dr. Lauren Westafer highlights the use of the ADD risk score combined with D-Dimer to safely rule out thoracic aortic dissection. Recent evidence indicates that COVID-19 antivirals offer minimal benefit for vaccinated, non-high-risk patients, while early basal insulin administration improves DKA resolution. Regarding pulmonary embolism, clinical guidelines now emphasize low-molecular-weight heparin over unfractionated heparin and advocate for echocardiography over CT for assessing right ventricular strain. Furthermore, the discussion challenges the efficacy of catheter-directed thrombolysis, noting that patient-oriented benefits remain unproven in recent trials. Finally, IV sodium bicarbonate emerges as a potential alternative to traditional antihistamines for managing acute peripheral vertigo, offering a treatment option that avoids the sedative side effects associated with standard vestibular suppressants.

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